BACKGROUND AND PURPOSE: Neurologic morbidity remains high in neonates with
perinatal hypoxic-ischemic injury despite therapeutic hypothermia. DTI provides qualitative …

Background Deviation of mean arterial blood pressure (MAP) from the range that optimizes
cerebral autoregulatory vasoreactivity (optimal MAP) could increase neurological injury from …

Despite improvements in obstetrical and neonatal care, and introduction of hypothermia as a
neuroprotective therapy, perinatal brain injury remains a frequent cause of cerebral palsy …

Background: Therapeutic hypothermia provides incomplete neuroprotection for neonatal
hypoxic-ischemic encephalopathy (HIE). We examined whether hemodynamic goals that …

Impaired cerebral autoregulation may contribute to secondary injury in newborns with
hypoxic-ischemic encephalopathy (HIE). Continuous, noninvasive assessment of cerebral …

Introduction: The preterm born infant's ability to regulate its cerebral blood flow (CBF) is
crucial in preventing secondary ischemic and hemorrhagic damage in the developing brain …

Background: Neonates with hypoxic–ischemic encephalopathy (HIE) are at risk of cerebral
blood flow dysregulation. Our objective was to describe the relationship between …

Background The measurement of brain perfusion may provide valuable information for
assessment and treatment of newborns with hypoxic–ischemic encephalopathy (HIE). While …

Biomarkers are required for efficient trials of neuroprotective interventions after perinatal
asphyxia. This study aimed to determine whether diffusion tensor imaging (DTI) analyzed by …

After hypoxic brain injury, maintaining blood pressure within the limits of cerebral blood flow
autoregulation is critical to preventing secondary brain injury. Little is known about the …