BACKGROUND AND PURPOSE: Sphenoid dysplasia associated with neurofibromatosis
type 1 is classically thought to be primarily related to abnormal development of the sphenoid …

We report two patients with abnormal development of the lesser wing of the sphenoid bone,
globe, optic nerve and cerebral hemisphere without stigmata of neurofibromatosis type 1 …

Abstract UNILATERAL ABSENCE OF the greater wing of the sphenoid bone is a distinctive
but uncommon manifestation of Type I neurofibromatosis, which has until now been …

Sphenoid wing dysplasia occurs in 3–7% of patients with neurofibromatosis type 1 (NF1).
The typical radiological features are partial or complete absence of the greater wing of the …

Object Skull defects, including sphenoid dysplasia and calvarial defects, are rare but distinct
findings in patients with neurofibromatosis Type 1 (NF1). The underlying pathophysiology is …

Osseous manifestations of neurofibromatosis 1 (NF-1) occur in a minority of the affected
subjects but may be because of significant clinical impairment. Typically, they involve the …

Cranio-orbital-temporal neurofibromatosis is an uncommon subtype of neurofibromatosis 1
characterized by pulsatile exophthalmos, orbital neurofibromas, sphenoid wing dysplasia …

BACKGROUND AND PURPOSE: The possible relationship of orbit deformities in
neurofibromatosis type 1 (NF1) to plexiform neurofibromas (PNFs) have not been fully …

Abstract Background Neurofibromatosis type 1 (NF1) is a common, autosomal dominant
tumor-predisposition disorder that arises secondary to mutations in the tumor suppressor …

Abstract Purpose Neurofibromatosis type 1 (NF1) is an autosomal dominant transmitted
tumour suppressor syndrome and also a bone disease. Osseous dysplasia affecting the …