BACKGROUND AND PURPOSE: The structural MR imaging correlates of cognitive
impairment in multiple sclerosis are still debated. This study assessed lesional and atrophy …

In a multicenter setting, we applied voxel‐based methods to different structural MR imaging
modalities to define the relative contributions of focal lesions, normal‐appearing white …

Objective: To investigate whether cognitive impairment in multiple sclerosis (MS) patients is
associated to different patterns of gray matter (GM) atrophy and T2‐visible lesion distribution …

Cognitive disorders occur in up to 65% of multiple sclerosis (MS) patients; they have been
correlated with different MRI measures of brain tissue damage, whole and regional brain …

Background: Cognitive deficits are common in multiple sclerosis. Most previous studies
investigating the imaging substrate of cognitive deficits in multiple sclerosis included …

Background Heterogeneous processes may contribute to cognitive impairment in multiple
sclerosis (MS). Objective To apply a longitudinal multiparametric MRI approach to identify …

Background Cognitive impairment frequently affects multiple sclerosis (MS) patients.
However, its neuroanatomical correlates still need to be fully explored. We investigated the …

Cognitive impairment is a frequent symptom in people with multiple sclerosis, affecting up to
70% of patients. This article reviews the published association of cognitive dysfunction with …

Purpose To investigate the discrepancy between patients with multiple sclerosis (MS)
without atrophy who have already developed cognitive impairment and patients with MS …

Objective To determine which pathologic process could be responsible for the acceleration
of cognitive decline during the course of multiple sclerosis (MS), using longitudinal structural …