Potential of T2 relaxation time measurements for early detection of radiation injury to the brain: experimental study in pigs.

E Miot-Noirault, S Akoka, D Hoffschir… - American journal …, 1996 - Am Soc Neuroradiology
PURPOSE To investigate the MR T2 relaxation time and histologic changes after a single-
fraction 25-Gy dose of radiation to the brain of pigs. METHODS The right hemisphere of 10 …

Experimental MR study of cerebral radiation injury: quantitative T2 changes over time and histopathologic correlation.

E Miot, D Hoffschir, C Alapetite… - American journal …, 1995 - Am Soc Neuroradiology
PURPOSE To use the pig brain as a large-animal model to examine the effects of high-dose
single-fraction irradiation on MR images, T2 relaxation time, and histologic integrity …

Quantitative magnetic resonance and isotopic imaging: early evaluation of radiation injury to the brain

E Miot, D Hoffschir, D Pontvert, G Gaboriaud… - International Journal of …, 1995 - Elsevier
Purpose: Using magnetic resonance (MR) and isotopic imaging to investigate the cerebral
alterations after high-dose single-fraction irradiation on a pig model. We assessed the …

Magnetic resonance imaging as a monitor of changes in the irradiated rat brain: An aid in determining the time course of events in a histologic study

AS Kennedy, MH ARCHAMBEAU… - Investigative …, 1995 - journals.lww.com
RATIONALE AND OBJECTIVES. Optimal dose schedules and total dose of ionizing
radiation for human central nervous system malignancy are not known. An animal model …

Regional T1 relaxation time constants in Ex vivo human brain: Longitudinal effects of formalin exposure

MR Raman, Y Shu, TG Lesnick… - Magnetic resonance …, 2017 - Wiley Online Library
Purpose Relaxation time constants are useful as markers of tissue properties. Imaging ex
vivo tissue is done for research purposes; however, T1 relaxation time constants are altered …

Comparison of different pulse sequences for in vivo determination of T1 relaxation times in the human brain

L Kjaer, O Henriksen - Acta Radiologica, 1988 - Taylor & Francis
Quantitative in vivo determination of T1 relaxation times by magnetic resonance imaging
(MRI) is hampered by several potential sources of error. This study focused on the influence …

Prediction of radiation necrosis in a rodent model using magnetic resonance imaging apparent transverse relaxation ()

JG Belliveau, MD Jensen, JMP Stewart… - Physics in Medicine …, 2018 - iopscience.iop.org
Background and purpose. Radiation necrosis remains an irreversible long-term side-effect
following radiotherapy to the brain. The ability to predict areas that could ultimately develop …

T relaxation and its application to MR histology

RT Engelhardt, GA Johnson - Magnetic resonance in medicine, 1996 - Wiley Online Library
The application of T1P as an alternative contrast parameter in high‐field magnetic
resonance histology (MRH) has been investigated. Spectroscopic measurements of T1P …

T2 estimates in healthy and diseased brain tissue: a comparison using various MR pulse sequences.

RH Darwin, BP Drayer, SJ Riederer, HZ Wang… - Radiology, 1986 - pubs.rsna.org
Fourteen patients and five healthy individuals underwent magnetic resonance (MR) imaging
to determine an effective multiple spin echo pulse sequence for estimating T2. Lesions …

Quantification and reproducibility assessment of the regional brain T2 relaxation in naïve rats at 7T

S Liachenko, J Ramu - Journal of Magnetic Resonance Imaging, 2017 - Wiley Online Library
Purpose To measure the reproducibility of T2 relaxation and to determine the statistical
power of T2 mapping in the rat brain as a characteristic of the baseline performance of the …