Metabolic abnormalities in the hippocampus of patients with schizophrenia: a 3D multivoxel MR spectroscopic imaging study at 3T
BACKGROUND AND PURPOSE: Schizophrenia is well-known to be associated with
hippocampal structural abnormalities. We used 1H-MR spectroscopy to test the hypothesis …
hippocampal structural abnormalities. We used 1H-MR spectroscopy to test the hypothesis …
Preliminary Findings Associate Hippocampal 1H-MR Spectroscopic Metabolite Concentrations with Psychotic and Manic Symptoms in Patients with Schizophrenia
BACKGROUND AND PURPOSE: Previous hippocampal proton MR spectroscopic imaging
distinguished patients with schizophrenia from controls by elevated Cr levels and …
distinguished patients with schizophrenia from controls by elevated Cr levels and …
Evidence for regional hippocampal damage in patients with schizophrenia
Purpose Schizophrenia patients show cognitive and mood impairments, including memory
loss and depression, suggesting damage in the brain regions. The hippocampus is a brain …
loss and depression, suggesting damage in the brain regions. The hippocampus is a brain …
Regionally specific pattern of neurochemical pathology in schizophrenia as assessed by multislice proton magnetic resonance spectroscopic imaging.
A Bertolino, S Nawroz, VS Mattay… - The American journal …, 1996 - europepmc.org
Objective Several single-voxel proton magnetic resonance spectroscopy (1H-MRS) studies
of patients with schizophrenia have found evidence of reductions of N-acetyl-aspartate …
of patients with schizophrenia have found evidence of reductions of N-acetyl-aspartate …
Regionally specific neuronal pathology in untreated patients with schizophrenia: a proton magnetic resonance spectroscopic imaging study
A Bertolino, JH Callicott, I Elman, VS Mattay… - Biological …, 1998 - Elsevier
Background: Proton magnetic resonance spectroscopic imaging (1H-MRSI) studies have
reported reductions of N-acetyl aspartate (NAA), a marker of neuronal integrity, in the …
reported reductions of N-acetyl aspartate (NAA), a marker of neuronal integrity, in the …
1H magnetic resonance spectroscopy characterization of neuronal dysfunction in drug-neive, chronic schizophrenia
BY Choe, KT Kim, TS Suh, C Lee, IH Paik, YW Bahk… - Academic radiology, 1994 - Elsevier
Rationale and Objectives. We in vestigated the proton metabolism of right prefrontal white
matter in drug-naive, chronic schizophrenic patients (n= 23), compared with healthy normal …
matter in drug-naive, chronic schizophrenic patients (n= 23), compared with healthy normal …
A fully automated method for tissue segmentation and CSF-correction of proton MRSI metabolites corroborates abnormal hippocampal NAA in schizophrenia
In this report, we describe the implementation and application of a fully automated
segmentation routine using SPM99 algorithms and MATLAB for clinical Magnetic …
segmentation routine using SPM99 algorithms and MATLAB for clinical Magnetic …
Hippocampal neuronal dysfunction in schizophrenia as measured by proton magnetic resonance spectroscopy
RF Deicken, L Zhou, N Schuff, G Fein, MW Weiner - Biological Psychiatry, 1998 - Elsevier
BACKGROUND:: Previous neuropathological and neuroimaging studies have documented
neuronal loss in the hippocampal region in schizophrenia. N-acetylaspartate (NAA) is a …
neuronal loss in the hippocampal region in schizophrenia. N-acetylaspartate (NAA) is a …
[HTML][HTML] Hippocampal pathology in schizophrenia: magnetic resonance imaging and spectroscopy studies
LS Kegeles, DC Shungu, S Anjilvel, S Chan… - Psychiatry Research …, 2000 - Elsevier
The hippocampus is a site of previously reported structural and functional abnormalities in
schizophrenia. We used magnetic resonance imaging (MRI) and proton magnetic …
schizophrenia. We used magnetic resonance imaging (MRI) and proton magnetic …
Schizophrenia, temporal lobe epilepsy and psychosis: an in vivo magnetic resonance spectroscopy and imaging study of the hippocampus/amygdala complex
M Maier, J Mellers, B Toone, M Trimble… - Psychological …, 2000 - cambridge.org
Background. We have used proton magnetic resonance imaging and spectroscopy to
measure hippocampus/amygdala volumes and anterior hippocampal metabolite …
measure hippocampus/amygdala volumes and anterior hippocampal metabolite …