BACKGROUND AND PURPOSE: Progressive changes in the substantia nigra pars
compacta and locus ceruleus of patients with Parkinson disease and Alzheimer disease …

Introduction Neuromelanin-sensitive MR imaging (MRI) can visualize neuromelanin-
containing neurons in the substantia nigra pars compacta (SNc), and its utility has been …

Purpose Neuromelanin-sensitive MR imaging (NMI) is an increasingly powerful tool for the
diagnosis of Parkinson's disease (PD). This study was undertaken to evaluate longitudinal …

BACKGROUND AND PURPOSE: Several new MR imaging techniques have shown
promising results in patients with Parkinson disease; however, the comparative diagnostic …

Background: Specific MR sequences have been able to identify the loss of neuromelanin in
the substantia nigra (SN) of early stage Parkinson's disease (PD) patients. Since this …

Pigmented neurons in the substantia nigra pars compacta (SNc) and locus coeruleus (LC)
show decreased numbers differentially in Parkinson's disease (PD) and multiple system …

We carried out an investigation to identify neuromelanin-containing noradrenergic and
dopaminergic neurons in the locus ceruleus and substantia nigra pars compacta of healthy …

Neuromelanin-sensitive magnetic resonance imaging is able to visualize changes
associated with neuronal loss in the substantia nigra pars compacta (SNc) and locus …

Introduction Several reports have shown that neuromelanin-sensitive magnetic resonance
imaging (NMI) using 3T magnetic resonance imaging is useful for the differential diagnosis …

Purpose The purpose of this study was to investigate whether the signal intensity of the
substantia nigra pars compacta (SNc) and locus coeruleus (LC) on neuromelanin-sensitive …