Semiautomated evaluation of the primary motor cortex in patients with amyotrophic lateral sclerosis at 3T

G Donatelli, A Retico, EC Ienco… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Amyotrophic lateral sclerosis is a neurodegenerative
disease involving the upper and lower motor neurons. In amyotrophic lateral sclerosis …

High-resolution 7T MR imaging of the motor cortex in amyotrophic lateral sclerosis

M Cosottini, G Donatelli, M Costagli… - American journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Amyotrophic lateral sclerosis is a progressive motor
neuron disorder that involves degeneration of both upper and lower motor neurons. In …

Quantitative susceptibility mapping of the motor cortex in amyotrophic lateral sclerosis and primary lateral sclerosis

AD Schweitzer, T Liu, A Gupta… - American journal of …, 2015 - Am Roentgen Ray Soc
OBJECTIVE. The diagnosis of amyotrophic lateral sclerosis (ALS) and primary lateral
sclerosis (PLS) is often difficult because of a lack of disease biomarkers. The purpose of this …

Upper motor neuron involvement in amyotrophic lateral sclerosis evaluated by triple stimulation technique and diffusion tensor MRI

J Furtula, B Johnsen, J Frandsen, A Rodell… - Journal of …, 2013 - Springer
The objective of this study was to evaluate the diagnostic value of triple stimulation
technique (TST) and diffusion tensor imaging (DTI) tractography as markers of upper motor …

The “motor band sign:” susceptibility-weighted imaging in amyotrophic lateral sclerosis

S Chakraborty, A Gupta, T Nguyen… - Canadian Journal of …, 2015 - cambridge.org
The diagnosis of amyotrophic lateral sclerosis (ALS) requires detection of both upper motor
neuron (UMN) and lower motor neuron (LMN) degeneration. Electromyography effectively …

[HTML][HTML] Diagnostic and prognostic value of conventional brain MRI in the clinical work-up of patients with amyotrophic lateral sclerosis

G Rizzo, AF Marliani, S Battaglia… - Journal of Clinical …, 2020 - mdpi.com
Clinical signs of upper motor neuron (UMN) involvement are important in the diagnosis of
amyotrophic lateral sclerosis (ALS) though are often difficult to analyze. Many studies using …

[HTML][HTML] Iron accumulation in deep cortical layers accounts for MRI signal abnormalities in ALS: correlating 7 tesla MRI and pathology

JY Kwan, SY Jeong, P Van Gelderen, HX Deng… - PloS one, 2012 - journals.plos.org
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder
characterized by cortical and spinal motor neuron dysfunction. Routine magnetic resonance …

[HTML][HTML] Magnetic susceptibility in the deep layers of the primary motor cortex in amyotrophic lateral sclerosis

M Costagli, G Donatelli, L Biagi, EC Ienco… - NeuroImage: Clinical, 2016 - Elsevier
Abstract Amyotrophic Lateral Sclerosis (ALS) is a progressive neurological disorder that
entails degeneration of both upper and lower motor neurons. The primary motor cortex (M1) …

Magnetic resonance imaging in amyotrophic lateral sclerosis

M Basak, M Erturk, B Oflazoglu, A Ozel… - Acta neurologica …, 2002 - Wiley Online Library
Objective–We aimed to investigate the importance of magnetic resonance imaging for the
diagnostic process of the upper motor neuron involvement. Material and methods–Fifteen …

Low signal intensity in motor cortex on susceptibility-weighted MR imaging is correlated with clinical signs of amyotrophic lateral sclerosis: a pilot study

H Endo, K Sekiguchi, H Shimada, T Ueda, H Kowa… - Journal of …, 2018 - Springer
There is no reliable objective indicator for upper motor neuron dysfunction in amyotrophic
lateral sclerosis (ALS). To determine the clinical significance and potential utility of magnetic …