Initial investigation into microbleeds and white matter signal changes following radiotherapy for low-grade and benign brain tumors using ultra-high-field MRI …

JG Belliveau, GS Bauman, KY Tay… - American Journal of …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: External beam radiation therapy is a common treatment
for many brain neoplasms. While external beam radiation therapy adheres to dose limits to …

Susceptibility-weighted MR imaging of radiation therapy-induced cerebral microbleeds in patients with glioma: a comparison between 3T and 7T

W Bian, CP Hess, SM Chang, SJ Nelson, JM Lupo - Neuroradiology, 2014 - Springer
Introduction Cerebral microbleeds have been observed in normal-appearing brain tissue of
patients with glioma years after receiving radiation therapy. The contrast of these …

Risk factors of radiotherapy‐induced cerebral microbleeds and serial analysis of their size compared with white matter changes: A 7T MRI study in 113 adult patients …

MA Morrison, CP Hess, JL Clarke… - Journal of Magnetic …, 2019 - Wiley Online Library
Background Although radiation therapy (RT) contributes to survival benefit in many brain
tumor patients, it has also been associated with long‐term brain injury. Cerebral …

[HTML][HTML] Relationship between radiation dose and microbleed formation in patients with malignant glioma

M Wahl, M Anwar, CP Hess, SM Chang, JM Lupo - Radiation Oncology, 2017 - Springer
Background Cranial irradiation is associated with long-term cognitive changes. Cerebral
microbleeds (CMBs) have been identified on susceptibility-weighted MRI (SWI) in patients …

The effects of anti-angiogenic therapy on the formation of radiation-induced microbleeds in normal brain tissue of patients with glioma

JM Lupo, AM Molinaro, E Essock-Burns… - Neuro …, 2015 - academic.oup.com
Background Radiotherapy (RT) is an integral component in managing patients with glioma,
but the damage it may cause to healthy brain tissue and quality of life is of concern …

Rate of radiation-induced microbleed formation on 7T MRI relates to cognitive impairment in young patients treated with radiation therapy for a brain tumor

MA Morrison, S Mueller, E Felton, A Jakary… - Radiotherapy and …, 2021 - Elsevier
Background Radiation therapy (RT) is essential to the management of many brain tumors,
but has been known to lead to cognitive decline and vascular injury in the form of cerebral …

Relationship between radiation dose and microbleed formation in patients with malignant glioma

M Wahl, M Anwar, C Hess, SM Chang… - International Journal of …, 2016 - redjournal.org
Results Thirteen of 14 patients exhibited CMBs, with a total of 311 individual CMBs
observed. The number of CMBs observed was significantly higher at late time points (early …

7-Tesla susceptibility-weighted imaging to assess the effects of radiotherapy on normal-appearing brain in patients with glioma

JM Lupo, CF Chuang, SM Chang, IJ Barani… - International Journal of …, 2012 - Elsevier
PURPOSE: To evaluate the intermediate-and long-term imaging manifestations of
radiotherapy on normal-appearing brain tissue in patients with treated gliomas using 7T …

[HTML][HTML] MR imaging evaluation of intracerebral hemorrhages and T2 hyperintense white matter lesions appearing after radiation therapy in adult patients with primary …

DH Yoo, SW Song, TJ Yun, TM Kim, SH Lee, JH Kim… - PLoS …, 2015 - journals.plos.org
The purpose of our study was to determine the frequency and severity of intracerebral
hemorrhages and T2 hyperintense white matter lesions (WMLs) following radiation therapy …

MRI changes due to early-delayed conformal radiotherapy and postsurgical effects in patients with brain tumors

CL Armstrong, JV Hunter, D Hackney… - International Journal of …, 2005 - Elsevier
Purpose: Discernment of radiotherapy (XRT) effects vs. tumor activity is difficult in brain
tumor patients during the months after XRT when white matter hyperintensities sometimes …