Volumetric analysis of structural MR images of the brain may provide quantitative evidence
of neurodegeneration and help identify patients at risk for rapid clinical deterioration. This …

We present global and regional rates of brain atrophy measured on serially acquired T1-
weighted brain MR images for a group of Alzheimer's disease (AD) patients and age …

We determined topographic selectivity and diagnostic utility of brain atrophy in probable
Alzheimer's disease (AD) and correlations with demographic factors such as age, sex, and …

Alzheimer's disease (AD) is characterized by progressive cerebral atrophy, which may be
assessed by using volumetric MRI. We describe a voxel-based analysis of nonlinear …

Magnetic resonance (MR) imaging can provide a longitudinal view of neurological disease
through repeated imaging of patients at successive stages of impairment. Until recently, the …

PURPOSE To compare brain tissue in patients with Alzheimer disease with that in elderly
control subjects by using high-resolution MR imaging and quantitative tissue-segmentation …

Purpose To determine whether automatic and manual measurements of hippocampal
volume differences on MRI between normal aging, cognitive impairment (CI), and …

The identification of structural changes in the brain on magnetic resonance imaging (MRI)
scans is increasingly important in the study of neurological and psychiatric diseases. MRI …

Clinical utility of magnetic resonance imaging (MRI) for the diagnosis and assessment of
neurodegenerative diseases may depend upon the reliability of MRI measurements …

Objectives: To test the applicability of an automated method of magnetic resonance image
analysis (voxel based morphometry) to detect presence and severity of regional grey matter …