I read with great interest the retrospective study by Hom et al, 1 in which a model combining
clinical metrics with blood-brain barrier (BBB) permeability data from dynamic CT was …

Thrombolytic therapy with recombinant tissue plasminogen activators (rtPA) is the main
treatment available for acute ischemic stroke, yet use of rtPA is currently limited to patients …

Objective We sought to examine the diagnostic utility of existing predictors of any
hemorrhagic transformation (HT) and compare them with new perfusion imaging …

BACKGROUND AND PURPOSE: The contrast volume transfer coefficient (K trans), which
reflects blood-brain barrier permeability, is influenced by circulation and measurement …

Purpose: To determine whether admission computed tomography (CT) perfusion–derived
permeability–surface area product (PS) maps differ between patients with hemorrhagic …

PURPOSE: Hemorrhagic transformation (HT) is a common consequence of infarction
independent of thrombolytic therapy. Our purpose was to examine if permeability imaging in …

BACKGROUND AND PURPOSE: Hemorrhagic transformation (HT) can be a devastating
complication of acute ischemic stroke (AIS). The purpose of this study was to determine …

BACKGROUND AND PURPOSE: SHT and ME are feared complications in patients with
acute ischemic stroke. They occur> 10 times more frequently in tPA-treated versus placebo …

BACKGROUND AND PURPOSE: Symptomatic hemorrhagic transformation (HT) is a
significant complication of intravenous and catheter-based reperfusion. We hypothesized …

Abstract Background and Purpose Parenchymal hematoma is a dreaded complication of
mechanical thrombectomy after acute ischemic stroke. This study evaluated whether blood …