Functional MR imaging using a visually guided saccade paradigm for comparing activation patterns in patients with probable Alzheimer's disease and in cognitively …

KR Thulborn, C Martin… - American Journal of …, 2000 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Alzheimer's disease is associated with progressive visuo-
spatial dysfunction. This study used functional MR (fMR) imaging with an eye movement …

The neural basis of visuospatial perception in Alzheimer's disease and healthy elderly comparison subjects: an fMRI study

SN Thiyagesh, TFD Farrow, RW Parks… - Psychiatry Research …, 2009 - Elsevier
The neural basis of visuospatial deficits in Alzheimer's disease is unclear. We wished to
investigate the neural basis of visuospatial perception in patients with Alzheimer's disease …

Functional imaging of visuospatial processing in Alzheimer's disease

D Prvulovic, D Hubl, AT Sack, L Melillo, K Maurer… - Neuroimage, 2002 - Elsevier
Alzheimer's disease (AD) is known to cause a variety of disturbances of higher visual
functions that are closely related to the neuropathological changes. Visual association areas …

FMRI of working memory in patients with mild cognitive impairment and probable Alzheimer's disease

FZ Yetkin, RN Rosenberg, MF Weiner, PD Purdy… - European …, 2006 - Springer
The goals of this study were to evaluate brain activation in patients with probable
Alzheimer's disease (AD), mild cognitive impairment (MCI), and controls while performing a …

Failure to modulate neural response to increased task demand in mild Alzheimer's disease: fMRI study of visuospatial processing

P Vannini, C Lehmann, T Dierks, K Jann… - Neurobiology of …, 2008 - Elsevier
Alzheimer's disease (AD) is characterized by disturbances of visuospatial cognition. Given
that these impairments are closely related to metabolic and neuropathological changes, our …

Functional MR imaging in Alzheimer's disease during memory encoding

SARB Rombouts, F Barkhof… - American Journal …, 2000 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: We applied functional MR imaging with a learning task in
healthy elderly volunteers and in patients with Alzheimer's disease to study brain activation …

Memory encoding in Alzheimer's disease: an fMRI study of explicit and implicit memory

A Golby, G Silverberg, E Race, S Gabrieli, J O'Shea… - Brain, 2005 - academic.oup.com
Alzheimer's disease is the most common cause of dementia in older adults. Although the
cognitive deficits and pathologic hallmarks of Alzheimer's disease have been well …

Functional imaging predicts cognitive decline in Alzheimer's disease

WJ Jagust, MN Haan, JL Eberling… - Journal of …, 1996 - Wiley Online Library
Eighteen patients with Alzheimer's disease were studied with positron emission tomographic
measurements of regional cerebral metabolism of glucose. All patients were initially …

Functional integration of parietal lobe activity in early Alzheimer disease

HIL Jacobs, MPJ Van Boxtel, A Heinecke… - Neurology, 2012 - AAN Enterprises
Objectives: Parietal lobe dysfunction is an important characteristic of early Alzheimer
disease (AD). Functional studies have shown conflicting parietal activation patterns …

Head motion parameters in fMRI differ between patients with mild cognitive impairment and Alzheimer disease versus elderly control subjects

S Haller, AU Monsch, J Richiardi, F Barkhof… - Brain topography, 2014 - Springer
Motion artifacts are a well-known and frequent limitation during neuroimaging workup of
cognitive decline. While head motion typically deteriorates image quality, we test the …