Hemodynamic response changes in cerebrovascular disease: implications for functional MR imaging

LM Carusone, J Srinivasan… - American Journal …, 2002 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Patients with cerebrovascular occlusive disease may
develop compensatory changes in local cerebral vasculature with a resultant loss of …

Altered hemodynamics and regional cerebral blood flow in patients with hemodynamically significant stenoses

AC Roc, J Wang, BM Ances, DS Liebeskind, SE Kasner… - Stroke, 2006 - Am Heart Assoc
Background and Purpose—Blood oxygen level–dependent (BOLD) contrast largely
depends on changes in cerebral blood flow (CBF). Because cerebrovascular disease may …

Invalidation of fMRI experiments secondary to neurovascular uncoupling in patients with cerebrovascular disease

AE Para, K Sam, J Poublanc, JA Fisher… - Journal of Magnetic …, 2017 - Wiley Online Library
Purpose Blood oxygen level‐dependent (BOLD) functional magnetic resonance imaging
(fMRI) is a technique used to infer neuronal activity from the observed changes in blood flow …

Impaired hemodynamic response in the ischemic brain assessed with BOLD fMRI

S Amemiya, A Kunimatsu, N Saito, K Ohtomo - Neuroimage, 2012 - Elsevier
The study aims to investigate the effect of cerebral ischemia or hypoperfusion in the
evaluation of neural activity with blood-oxygen-level dependent (BOLD) functional magnetic …

The influence of extra-and intracranial artery disease on the BOLD signal in FMRI

F Hamzei, R Knab, C Weiller, J Röther - Neuroimage, 2003 - Elsevier
Functional MRI is based on the vascular response due to neuronal activation. The
underlying mechanism of fMRI is the blood oxygenation level-dependent (BOLD) effect—a …

Mapping cerebrovascular reactivity using blood oxygen level-dependent MRI in patients with arterial steno-occlusive disease: comparison with arterial spin labeling …

DM Mandell, JS Han, J Poublanc, AP Crawley… - Stroke, 2008 - Am Heart Assoc
Background and Purpose—Blood oxygen level-dependent MRI (BOLD MRI) of hypercapnia-
induced changes in cerebral blood flow is an emerging technique for mapping …

Mapping of cerebrovascular reactivity using BOLD magnetic resonance imaging

DJ Lythgoe, SCR Williams, M Cullinane… - Magnetic resonance …, 1999 - Elsevier
Blood oxygen level-dependent (BOLD) contrast MRI is a simple non-invasive method of
estimating “perfusion,” and combined with a vasodilatory stimulus, may allow estimation of …

Neuronal activation induced BOLD and CBF responses upon acetazolamide administration in patients with steno-occlusive artery disease

JCW Siero, NS Hartkamp, MJ Donahue, AA Harteveld… - Neuroimage, 2015 - Elsevier
Abstract Blood-oxygenation-level-dependent (BOLD) MRI is widely used for inferring
neuronal activation and is becoming increasingly popular for assessing cerebrovascular …

Altered hemodynamic responses in patients after subcortical stroke measured by functional MRI

R Pineiro, S Pendlebury, H Johansen-Berg… - stroke, 2002 - Am Heart Assoc
Background and Purpose—Blood oxygenation level–dependent (BOLD) functional MRI
(fMRI) is a promising method for defining brain recovery after stroke quantitatively …

Assessment of cerebral blood flow reserve using functional magnetic resonance imaging

P Hedera, S Lai, JS Lewin, EM Haacke… - Journal of Magnetic …, 1996 - Wiley Online Library
Imaging of activated brain areas based on changes of blood deoxyhemoglobin levels is now
possible with MRI. Acetazolamide (ACZ) increases cerebral blood flow (CBF) without …