PURPOSE To establish whether regional disturbances of the benzodiazepine receptor
distribution in focal epilepsies can be detected by SPECT using 123-I-Iomazenil. PATIENTS …

Fifteen patients with therapy resistant partial complex seizures with no structural lesions
were examined interictally with 123‐I‐IOMAZENIL SPECT for measurement of …

Single photon emission computed tomography (SPECT) is being increasingly used as an
adjunctive technique in the localisation of epileptogenic foci prior to surgery. Fourteen …

Despite optimal pharmacotherapy, about 30% of patients with focal epilepsies arising from
the temporal lobe are frequently refractory to anticonvulsant medication (Schmidt, 1981). Up …

It was the aim of this study to compare benzodiazepine (Bz) receptor binding and cerebral
perfusion in patients with partial epilepsy. Single photon emission tomography (SPET) …

We examined the relation between regional 123 I-iomazenil (IMZ) parameters and cerebral
blood flow (CBF) to evaluate the difference between the quantitative parameters of IMZ and …

Fourteen patients with temporal lobe epilepsy, 9 patients after amygdalohippocampectomy
and 3 healthy volunteers were examined with the new benzodiazepine receptor marker 123l …

A phase 2 clinical study of 123I-iomazenil (IMZ) was performed to evaluate its clinical
usefulness as central-type benzodiazepine receptor imaging agent in 81 cases with …

123I‐iomazenil SPECT is of value in determining an epileptogenic focus, however, transient
uptake change has been rarely reported in epileptic disorders. A 78‐year‐old woman …

The ability of SPECT measurements with [99mTc]–HM-PAO (Ceretec) to find the location of
the epileptic focus was studied in patients under consideration for neurosurgical treatment …