Perfusion MRI-based fractional tumor burden differentiates between tumor and treatment effect in recurrent glioblastomas and informs clinical decision-making

M Iv, X Liu, J Lavezo, AJ Gentles… - American Journal …, 2019 - Am Soc Neuroradiology
Background and Purpose Fractional tumor burden better correlates with histologic tumor
volume fraction in treated glioblastoma than other perfusion metrics such as relative CBV …

Reevaluating the imaging definition of tumor progression: perfusion MRI quantifies recurrent glioblastoma tumor fraction, pseudoprogression, and radiation necrosis to …

LS Hu, JM Eschbacher, JE Heiserman… - Neuro …, 2012 - academic.oup.com
Abstract INTRODUCTION: Contrast-enhanced MRI (CE-MRI) represents the current
mainstay for monitoring treatment response in glioblastoma multiforme (GBM), based on the …

Impact of software modeling on the accuracy of perfusion MRI in glioma

LS Hu, Z Kelm, P Korfiatis, AC Dueck… - American Journal …, 2015 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Relative cerebral blood volume, as measured by T2*-
weighted dynamic susceptibility-weighted contrast-enhanced MRI, represents the most …

Combining perfusion and high B-value diffusion MRI to inform prognosis and predict failure patterns in glioblastoma

DR Wahl, MM Kim, MP Aryal, H Hartman… - International Journal of …, 2018 - Elsevier
Purpose Advanced imaging modalities such as high b-value diffusion and dynamic contrast
enhancement magnetic resonance imaging have the potential to improve the clinical …

Performance of standardized relative CBV for quantifying regional histologic tumor burden in recurrent high-grade glioma: comparison against normalized relative …

JM Hoxworth, JM Eschbacher… - American Journal …, 2020 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Perfusion MR imaging measures of relative CBV can
distinguish recurrent tumor from posttreatment radiation effects in high-grade gliomas …

Diffusion and perfusion MRI to differentiate treatment-related changes including pseudoprogression from recurrent tumors in high-grade gliomas with histopathologic …

AJ Prager, N Martinez, K Beal… - American Journal …, 2015 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Treatment-related changes and recurrent tumors often
have overlapping features on conventional MR imaging. The purpose of this study was to …

Clinical parameters outweigh diffusion-and perfusion-derived MRI parameters in predicting survival in newly diagnosed glioblastoma

S Burth, P Kickingereder, O Eidel, D Tichy… - Neuro …, 2016 - academic.oup.com
Background The purpose of this study was to determine the relevance of clinical data,
apparent diffusion coefficient (ADC), and relative cerebral blood volume (rCBV) from …

Identification of a candidate biomarker from perfusion MRI to anticipate glioblastoma progression after chemoradiation

J Khalifa, F Tensaouti, L Chaltiel, JA Lotterie… - European …, 2016 - Springer
Objective To identify relevant relative cerebral blood volume biomarkers from T2* dynamic-
susceptibility contrast magnetic resonance imaging to anticipate glioblastoma progression …

Perfusion MRI in the evaluation of suspected glioblastoma recurrence

S Blasel, A Zagorcic, A Jurcoane, O Bähr… - Journal of …, 2016 - Wiley Online Library
ABSTRACT PURPOSE Treatment‐related changes (TRC) often imitate tumor progression in
glioblastomas. Increased regional cerebral blood volume (rCBV) can differentiate tumor …

Perfusion magnetic resonance imaging predicts patient outcome as an adjunct to histopathology: a second reference standard in the surgical and nonsurgical …

M Law, S Oh, G Johnson, JS Babb, D Zagzag… - …, 2006 - journals.lww.com
OBJECTIVE: To determine whether relative cerebral blood volume (rCBV) can predict
patient outcome, specifically tumor progression, in low-grade gliomas (LGGs) and thus …