BACKGROUND AND PURPOSE: Early stratification of degenerative processes is a
prerequisite to warrant therapeutic options in prodromal Alzheimer disease. Our aim was to …

Multi-parametric and quantitative magnetic resonance imaging (MRI) techniques have come
into the focus of interest, both as a research and diagnostic modality for the evaluation of …

Almost half of the elderly subjects that are diagnosed with mild cognitive impairment (MCI)
go on to develop dementia of Alzheimer's type (DAT) over a 5-year follow-up. MCI and DAT …

OBJECTIVE: To assess whether structural brain damage as detected by magnetization
transfer imaging (MTI) in Alzheimer's disease (AD) and mild cognitive impairment (MCI) is …

BACKGROUND AND PURPOSE: Previous studies have shown involvement of both gray
matter (GM) and white matter (WM) in mild cognitive impairment (MCI) and Alzheimer …

BACKGROUND AND PURPOSE: MTI has been proposed as a sensitive technique for
studying microstructural brain tissue changes in patients with AD, but the course of these …

Purpose: To prospectively measure magnetization transfer (MT) parameters, along with
established atrophy parameters, in patients with Alzheimer disease (AD) and in age-and sex …

BACKGROUND AND PURPOSE: Reductions in magnetization transfer ratio have been
associated with brain microstructural damage. We aim to compare magnetization transfer …

The purpose of this study was to assess whether structural brain damage as detected by
volumetric magnetization transfer imaging (MTI) is present in mild cognitive impairment …

BACKGROUND AND PURPOSE: Manually drawn VOI-based analysis shows a decrease in
magnetization transfer ratio in the hippocampus of patients with Alzheimer disease. We …