Quantifying T2-FLAIR mismatch using geographically weighted regression and predicting molecular status in lower-grade gliomas

S Mohammed, V Ravikumar… - American Journal …, 2022 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The T2-FLAIR mismatch sign is a validated imaging sign
of isocitrate dehydrogenase–mutant 1p/19q noncodeleted gliomas. It is identified by …

The T2-FLAIR–mismatch sign as an imaging biomarker for IDH and 1p/19q status in diffuse low-grade gliomas: a systematic review with a Bayesian approach to …

A Goyal, YU Yolcu, A Goyal, P Kerezoudis… - Neurosurgical …, 2019 - thejns.org
OBJECTIVE With the revised WHO 2016 classification of brain tumors, there has been
increasing interest in imaging biomarkers to predict molecular status and improve the yield …

Association of partial T2-FLAIR mismatch sign and isocitrate dehydrogenase mutation in WHO grade 4 gliomas: results from the ReSPOND consortium

MD Lee, SH Patel, S Mohan, H Akbari, S Bakas… - Neuroradiology, 2023 - Springer
Abstract Purpose While the T2-FLAIR mismatch sign is highly specific for isocitrate
dehydrogenase (IDH)-mutant, 1p/19q-noncodeleted astrocytomas among lower-grade …

T2-fluid-attenuated inversion recovery mismatch sign in lower grade gliomas: correlation with pathological and molecular findings

S Yamashita, H Takeshima, Y Kadota, M Azuma… - Brain Tumor …, 2022 - Springer
After the new molecular-based classification was reported to be useful for predicting
prognosis, the T2-fluid-attenuated inversion recovery (FLAIR) mismatch sign has gained …

The T2-FLAIR mismatch sign as a predictor of IDH-mutant, 1p/19q-noncodeleted lower-grade gliomas: a systematic review and diagnostic meta-analysis

SI Park, CH Suh, JP Guenette, RY Huang, HS Kim - European radiology, 2021 - Springer
Objectives To evaluate the diagnostic performance of the T2-FLAIR mismatch sign for
prediction of isocitrate dehydrogenase (IDH)-mutant, 1p/19q-noncodeleted lower-grade …

Characterisation of isocitrate dehydrogenase gene mutant WHO grade 2 and 3 gliomas: MRI predictors of 1p/19q co-deletion and tumour grade

D Doig, C Kachramanoglou, M Dumba, F Tona… - Clinical Radiology, 2021 - Elsevier
AIM To identify imaging predictors of molecular subtype and tumour grade in patients with
isocitrate dehydrogenase (IDH) gene mutant (IDH mut) World Health Organization (WHO) …

“Real world” use of a highly reliable imaging sign:“T2-FLAIR mismatch” for identification of IDH mutant astrocytomas

R Jain, DR Johnson, SH Patel, M Castillo… - Neuro …, 2020 - academic.oup.com
AbstractThe T2-FLAIR (fluid attenuated inversion recovery) mismatch sign is an easily
detectable imaging sign on routine clinical MRI studies that suggests diagnosis of isocitrate …

T2/FLAIR-mismatch sign for noninvasive detection of IDH-mutant 1p/19q non-codeleted gliomas: validity and pathophysiology

M Foltyn, KN Nieto Taborda, U Neuberger… - Neuro-oncology …, 2020 - academic.oup.com
Background This study aimed to assess the validity and pathophysiology of the T2/FLAIR-
mismatch sign for noninvasive identification of isocitrate dehydrogenase (IDH)-mutant …

[HTML][HTML] Multi-parametric radiomic model to predict 1p/19q co-deletion in patients with IDH-1 mutant glioma: added value to the T2-FLAIR mismatch sign

S Kihira, A Derakhshani, M Leung, K Mahmoudi… - Cancers, 2023 - mdpi.com
Simple Summary The T2-FLAIR mismatch sign has shown promise in determining IDH
mutant 1p/19q non-co-deleted diffuse gliomas with a high specificity and modest sensitivity …

Radiogenomic association between the T2-FLAIR mismatch sign and IDH mutation status in adult patients with lower-grade gliomas: an updated systematic review …

Z Han, Q Chen, L Zhang, X Mo, J You, L Chen… - European …, 2022 - Springer
Objectives To reveal a radiogenomic correlation between the presence of the T2-fluid-
attenuated inversion recovery resection (T2-FLAIR) mismatch sign on MR images and …