Two pediatric patients with diffuse pontine tumors underwent MR spectroscopic imaging pre-
and postradiation. Choline/creatine (Cho/Cr) and Cho/N-acetylaspartate (NAA) ratios were …

Purpose To use multimodal magnetic resonance imaging (MRI) to quantify treatment-
induced changes in the whole volume of diffuse infiltrating pontine gliomas and correlate …

Object Diffuse pontine gliomas in children carry a dismal prognosis, with a mean survival of
less than 1 year despite therapy. The diagnosis is based on the characteristic changes …

Background: Pontine tumors carry the worst prognosis of all brain tumors. In most cases, the
diagnosis is based solely on MR imaging, without biopsy. Objective: To describe the MR …

Background Diffuse pontine glioma is a pediatric brain tumor with a median survival time of
1 year and few long-term survivors. Conventional MRI has not been shown to predict overall …

Patients with diffuse intrinsic pontine glioma (DIPG) face a grim prognosis with limited
treatment options. Many patients will enroll on investigational trials though the role of …

PURPOSE: To determine the feasibility of two magnetic resonance spectroscopy (MRS)
techniques for treating pediatric patients with diffuse intrinsic pontine gliomas (DIPGs) and to …

Background and Purpose: After radiotherapy (RT), children with diffuse intrinsic pontine
gliomas (DIPG) are followed with sequential magnetic resonance imaging (MRI). However …

BACKGROUND In vivo biomarkers to predict progression of brain tumors are of great value
in clinical practice. Therefore, the authors tested the hypothesis that changes in choline …

Although tumors of the brain stem have traditionally been classified as a single entity, these
tumors are increasingly being recognized as a heterogeneous group, with some subgroups …