The documentation and characterization of treatment-related neurotoxicity in primary CNS
lymphoma (PCNSL) and other brain tumor patients have become increasingly relevant as …

Background Treatment for primary central nervous lymphoma (PCNSL) with chemotherapy
and radiotherapy has resulted in improved survival, but some patients develop neurologic …

Primary CNS lymphoma (PCNSL) is an uncommon type of extranodal non-Hodgkin
lymphoma confined to the brain, leptomeninges, or eyes. Although more than 90% of …

1530 Background: A phase II trial was designed to assess MATILDE chemotherapy (CHT)
regimen in untreated PCNSL pts. This combination includes drugs active in different phases …

Purpose We previously reported a series of patients treated with high-dose methotrexate
(MTX)-based chemotherapy, with or without whole brain radiotherapy. The purpose of this …

Introduction: Optimal management of primary central nervous system lymphoma (PCNSL) is
controversial. Although there is widespread agreement that methotrexate is the most active …

To estimate the value of whole brain radiotherapy (WBRT) in the treatment of primary CNS
lymphoma (PCNSL), it is important to recall the goals of treatment when confronted with this …

Soon after primary CNS lymphoma (PCNSL) became identified as a treatable tumor,
patients, their families, and the treating physicians became aware of the neurocognitive toll …

Purpose Recently, reduced-dose whole-brain radiotherapy (WBRT) has been used to treat
primary central nervous system lymphoma (PCNSL). However, whether reduced-dose …

Primary central nervous system lymphoma (PCNSL) is a multifocal, in-filtrative tumor most
commonly located in the periventricular region and subcortical gray matter [1]. Currently …