Final cerebral infarct volume is predictable by MR imaging at 1 week

T Tourdias, P Renou, I Sibon… - American Journal …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Stroke volume, an increasingly used end point in phase II
trials, is considered stationary at least 30 days after the ictus. We investigated whether …

Establishing final infarct volume: stroke lesion evolution past 30 days is insignificant

MR Gaudinski, EC Henning, A Miracle, M Luby… - Stroke, 2008 - Am Heart Assoc
Background and Purpose—Lesion volume measured on MRI has been used as an objective
surrogate marker for outcome in clinical trials. However, lesion volumes vary over time …

Initial lesion volume is an independent predictor of clinical stroke outcome at day 90: an analysis of the Virtual International Stroke Trials Archive (VISTA) database

G Vogt, R Laage, A Shuaib, A Schneider - Stroke, 2012 - Am Heart Assoc
Background and Purpose—Age and National Institutes of Health Stroke Scale early after
stroke onset have been identified as important determinants of final stroke outcome. We …

[HTML][HTML] Final infarct volume estimation on 1-week follow-up MR imaging is feasible and is dependent on recanalization status

M Krongold, MA Almekhlafi, AM Demchuk, SB Coutts… - NeuroImage: Clinical, 2015 - Elsevier
Purpose We aim to characterize infarct volume evolution within the first month post-ischemic
stroke and to determine the effect of recanalization status on early infarct volume estimation …

Final infarct size after acute stroke: prediction with flow heterogeneity

CZ Simonsen, L Røhl, P Vestergaard-Poulsen… - Radiology, 2002 - pubs.rsna.org
PURPOSE: To compare acute measurements of flow heterogeneity (FH) and mean transit
time (MTT) with follow-up data to determine which method yields better predictive measures …

Measurement of infarct size using MRI predicts prognosis in middle cerebral artery infarction

DE Saunders, AG Clifton, MM Brown - Stroke, 1995 - Am Heart Assoc
Background and Purpose An accurate measure of the severity of ischemic insult and the
resulting prognosis is needed to assess the effectiveness of new treatments for acute stroke …

Final infarct volume discriminates outcome in mild strokes

AS Vagal, H Sucharew… - The Neuroradiology …, 2015 - journals.sagepub.com
Introduction Knowledge of whether final infarct volume (FIV) predicts disability after mild
stroke is limited. We sought to determine if FIV could differentiate good versus poor outcome …

Inter‐and intraobserver reliability of five MRI sequences in the evaluation of the final volume of cerebral infarct

I Sibon, P Ménégon, JM Orgogozo… - Journal of Magnetic …, 2009 - Wiley Online Library
Purpose To evaluate the reproducibility of fluid attenuated inversion recovery (FLAIR) and
four other magnetic resonance imaging (MRI) sequences in the quantitative assessment of …

Prediction of final infarct volume on subacute MRI by quantifying cerebral edema in ischemic stroke

A Tipirneni-Sajja, S Christensen… - Journal of Cerebral …, 2017 - journals.sagepub.com
Final infarct volume in stroke trials is assessed on images obtained between 30 and 90 days
after stroke onset. Imaging at such delayed timepoints is problematic because patients may …

Early change in stroke size performs best in predicting response to therapy

AN Simpkins, C Dias, G Norato, E Kim… - Cerebrovascular …, 2017 - karger.com
Background: Reliable imaging biomarkers of response to therapy in acute stroke are
needed. The final infarct volume and percent of early reperfusion have been used for this …