BACKGROUND AND PURPOSE: Texture analysis is an image processing technique that
can be used to extract parameters able to describe meaningful features of an image or ROI …

Friedreich ataxia is a progressive neurodegenerative disorder characterized by cerebellar
and spinal atrophy. However, studies to elucidate the longitudinal progression of the …

Background Friedreich ataxia is an inherited neurodegenerative disease, with cerebral and
cerebellar pathology evident. Despite an increased understanding of its neuropathology …

ABSTRACT BACKGROUND AND PURPOSE Imaging biomarkers of disease progression
are desirable in inherited ataxias. MRI has demonstrated brain damage in Friedreich ataxia …

Objective: Neuropathological descriptions of the brain in Friedreich's ataxia (FRDA) were
obtained before availability of the current molecular genetic tests for this disease. Voxel …

BACKGROUND AND PURPOSE:: Neuropathological examination in Friedreich ataxia
(FRDA) reveals neuronal loss in the gray matter (GM) nuclei and degeneration of the white …

Introduction Friedreich's ataxia (FRDA) is the most common autosomal‐recessive ataxia
worldwide. It is characterized by early onset, sensory abnormalities, and slowly progressive …

Friedreich's ataxia (FA) is the most frequent autosomal recessive ataxia and essentially
considered a disease of the dorsal root ganglia and spinal cord. It is caused by homozygous …

Friedreich ataxia is a progressive neurodegenerative disorder with reported abnormalities in
cerebellar, brainstem, and cerebral white matter. White matter structure can be measured …

Introduction Friedreich's ataxia (FRDA) is the most common hereditary ataxia and thinning of
the cervical spinal cord is a consistent observation in Magnetic resonance imaging (MRI) …