Comparison of ultrasmall particles of iron oxide (USPIO)-enhanced T2-weighted, conventional T2-weighted, and gadolinium-enhanced T1-weighted MR images in …
V Dousset, L Ballarino, C Delalande… - American journal …, 1999 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Ultrasmall particles of iron oxide (USPIO) constitute a
contrast agent that accumulates in cells from the mononuclear phagocytic system. In the …
contrast agent that accumulates in cells from the mononuclear phagocytic system. In the …
MR imaging of relapsing multiple sclerosis patients using ultra-small-particle iron oxide and compared with gadolinium
V Dousset, B Brochet, MSA Deloire… - American journal …, 2006 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Inflammatory multiple sclerosis (MS) lesions are
characterized by microglia activation and infiltration of T cells, B cells, and macrophages …
characterized by microglia activation and infiltration of T cells, B cells, and macrophages …
Imaging of inflammation in the peripheral and central nervous system by magnetic resonance imaging
G Stoll, M Bendszus - Neuroscience, 2009 - Elsevier
Inflammation plays a central role in the pathophysiology of numerous disorders of the
nervous system, but is also pivotal for repair processes like peripheral nerve regeneration. In …
nervous system, but is also pivotal for repair processes like peripheral nerve regeneration. In …
Dose and scanning delay using USPIO for central nervous system macrophage imaging
V Dousset, C Gomez, KG Petry, C Delalande… - … Resonance Materials in …, 1999 - Springer
Rationale and objectives: In experimental allergic encephalomyelitis (EAE), central nervous
system (CNS) macrophage imaging is achievable by MRI using AMI-227 an ultra-small …
system (CNS) macrophage imaging is achievable by MRI using AMI-227 an ultra-small …
Pluriformity of inflammation in multiple sclerosis shown by ultra-small iron oxide particle enhancement
MM Vellinga, RD Oude Engberink, A Seewann… - Brain, 2008 - academic.oup.com
Abstract Gadolinium-DTPA (Gd-DTPA) is routinely used as a marker for inflammation in MRI
to visualize breakdown of the blood–brain barrier (BBB) in multiple sclerosis. Recent data …
to visualize breakdown of the blood–brain barrier (BBB) in multiple sclerosis. Recent data …
Dynamics and fate of USPIO in the central nervous system in experimental autoimmune encephalomyelitis
RD Oude Engberink, ELA Blezer… - NMR in …, 2010 - Wiley Online Library
Signal loss observed in the brain by MRI following the administration of ultrasmall
superparamagnetic particles of iron oxide (USPIO) has been correlated with immune cell …
superparamagnetic particles of iron oxide (USPIO) has been correlated with immune cell …
Histochemical detection of ultrasmall superparamagnetic iron oxide (USPIO) contrast medium uptake in experimental brain ischemia
M Schroeter, A Saleh, D Wiedermann… - … in Medicine: An …, 2004 - Wiley Online Library
Recently, macrophage infiltration in different central nervous system (CNS) pathologies has
been visualized with ultrasmall particles of iron oxide (USPIO) as a new cell‐specific …
been visualized with ultrasmall particles of iron oxide (USPIO) as a new cell‐specific …
MRI of monocyte infiltration in an animal model of neuroinflammation using SPIO-labeled monocytes or free USPIO
RD Oude Engberink, ELA Blezer… - Journal of Cerebral …, 2008 - journals.sagepub.com
Magnetic resonance imaging (MRI) has been applied to visualize monocyte infiltration with
the use of intravenously injected ultrasmall superparamagnetic iron oxide (USPIO) …
the use of intravenously injected ultrasmall superparamagnetic iron oxide (USPIO) …
Iron‐oxide labeling of hematogenous macrophages in a model of experimental autoimmune encephalomyelitis and the contribution to signal loss in fast imaging …
AJ Oweida, EA Dunn, SJ Karlik… - Journal of Magnetic …, 2007 - Wiley Online Library
Purpose To determine the contribution of blood‐derived macrophages to the signal loss
observed in MR images of inflammatory lesions in experimental autoimmune …
observed in MR images of inflammatory lesions in experimental autoimmune …
Visualisation of the kinetics of macrophage infiltration during experimental autoimmune encephalomyelitis by magnetic resonance imaging
K Baeten, JJA Hendriks, N Hellings… - Journal of …, 2008 - Elsevier
Macrophages are considered to be the predominant effector cells in multiple sclerosis (MS)
and its animal model experimental autoimmune encephalomyelitis (EAE). Ultra small …
and its animal model experimental autoimmune encephalomyelitis (EAE). Ultra small …
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