Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Publication Preview--Ahead of Print
    • Past Issue Archive
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
    • COVID-19 Content and Resources
  • For Authors
  • About Us
    • About AJNR
    • Editors
    • American Society of Neuroradiology
  • Submit a Manuscript
  • Podcasts
    • Subscribe on iTunes
    • Subscribe on Stitcher
  • More
    • Subscribers
    • Permissions
    • Advertisers
    • Alerts
    • Feedback
  • Other Publications
    • ajnr

User menu

  • Subscribe
  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

  • Subscribe
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Publication Preview--Ahead of Print
    • Past Issue Archive
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
    • COVID-19 Content and Resources
  • For Authors
  • About Us
    • About AJNR
    • Editors
    • American Society of Neuroradiology
  • Submit a Manuscript
  • Podcasts
    • Subscribe on iTunes
    • Subscribe on Stitcher
  • More
    • Subscribers
    • Permissions
    • Advertisers
    • Alerts
    • Feedback
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds
Abstract

MR of hereditary hemorrhagic telangiectasia: prevalence and spectrum of cerebrovascular malformations.

R K Fulbright, J C Chaloupka, C M Putman, G K Sze, M M Merriam, G K Lee, P B Fayad, I A Awad and R I White
American Journal of Neuroradiology March 1998, 19 (3) 477-484;
R K Fulbright
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
J C Chaloupka
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
C M Putman
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
G K Sze
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M M Merriam
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
G K Lee
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
P B Fayad
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
I A Awad
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
R I White Jr
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
  • PDF
Loading

Abstract

PURPOSE Our goal was to describe the prevalence and types of cerebral vascular malformations (CVMs) seen with MR imaging in patients with hereditary hemorrhagic telangiectasia (HHT).

METHODS We reviewed retrospectively the brain MR images of 184 consecutive patients with HHT. Catheter angiography was performed in 17 patients with CVMs detected on MR images.

RESULTS MR imaging revealed 63 CVMs in 42 patients. Classic arteriovenous malformations (n = 10) had a conspicuous network of vessels with flow voids and enlarged adjacent pial vessels. Apparent venous malformations (n = 5) were best seen after administration of contrast material as a prominent vessel coursing through normal brain parenchyma. Indeterminate vascular malformations (n = 48) had a spectrum of appearances characterized by variable combinations of heterogeneous signal intensity, enhancement, or hemosiderin. Angiography in 17 patients revealed 47 CVMs. Forty-six were arteriovenous malformations (AVMs), including 25 CVMs not seen with MR imaging and 21 CVMs that by MR criteria included 8 AVMs and 13 indeterminate vascular malformations. Angiography confirmed 1 venous malformation seen with MR imaging but failed to detect 3 indeterminate lesions revealed by MR imaging.

CONCLUSION MR imaging of a large cohort of consecutive patients with HHT revealed a CVM prevalence of 23% (42/184). Most CVMs (48/63) have an atypical appearance for vascular malformations on MR images. Angiographic correlation suggests that MR imaging underestimates the prevalence of CVMs and that the majority of indeterminate CVMs, despite their variable MR appearance, are AVMs.

  • Copyright © American Society of Neuroradiology
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology
Vol. 19, Issue 3
1 Mar 1998
  • Table of Contents
  • Index by author
Advertisement
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
MR of hereditary hemorrhagic telangiectasia: prevalence and spectrum of cerebrovascular malformations.
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
MR of hereditary hemorrhagic telangiectasia: prevalence and spectrum of cerebrovascular malformations.
R K Fulbright, J C Chaloupka, C M Putman, G K Sze, M M Merriam, G K Lee, P B Fayad, I A Awad, R I White
American Journal of Neuroradiology Mar 1998, 19 (3) 477-484;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
MR of hereditary hemorrhagic telangiectasia: prevalence and spectrum of cerebrovascular malformations.
R K Fulbright, J C Chaloupka, C M Putman, G K Sze, M M Merriam, G K Lee, P B Fayad, I A Awad, R I White
American Journal of Neuroradiology Mar 1998, 19 (3) 477-484;
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Comparison of MRI, MRA, and DSA for Detection of Cerebral Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia
  • A theory for polymicrogyria and brain arteriovenous malformations in HHT
  • The Prevalence of Malformations of Cortical Development in a Pediatric Hereditary Hemorrhagic Telangiectasia Population
  • Cerebrovascular Manifestations of Hereditary Hemorrhagic Telangiectasia
  • Neurovascular Manifestations in Hereditary Hemorrhagic Telangiectasia: Imaging Features and Genotype-Phenotype Correlations
  • Rare manifestations in a case of Osler-Weber-Rendu disease
  • Brain Arteriovenous Malformation Multiplicity Predicts the Diagnosis of Hereditary Hemorrhagic Telangiectasia: Quantitative Assessment
  • International guidelines for the diagnosis and management of hereditary haemorrhagic telangiectasia
  • Genotype-phenotype relationship in hereditary haemorrhagic telangiectasia
  • Visceral manifestations in hereditary haemorrhagic telangiectasia type 2
  • Should asymptomatic patients with hereditary haemorrhagic telangiectasia (HHT) be screened for cerebral vascular malformations? Data from 22 061 years of HHT patient life
  • Cerebral Vascular Abnormalities in a Murine Model of Hereditary Hemorrhagic Telangiectasia
  • Hereditary haemorrhagic telangiectasia (Osler-Weber-Rendu syndrome): a view from the 21st century
  • Intracranial Hemorrhage in Infants and Children With Hereditary Hemorrhagic Telangiectasia (Osler-Weber-Rendu Syndrome)
  • Compelling Reasons to Screen Brain in HHT Response
  • Cerebrovascular Manifestations in 321 Cases of Hereditary Hemorrhagic Telangiectasia
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

Similar Articles

Advertisement

News and Updates

  • Lucien Levy Best Research Article Award
  • Thanks to our 2022 Distinguished Reviewers
  • Press Releases

Resources

  • Evidence-Based Medicine Level Guide
  • How to Participate in a Tweet Chat
  • AJNR Podcast Archive
  • Ideas for Publicizing Your Research
  • Librarian Resources
  • Terms and Conditions

Opportunities

  • Share Your Art in Perspectives
  • Get Peer Review Credit from Publons
  • Moderate a Tweet Chat

American Society of Neuroradiology

  • Neurographics
  • ASNR Annual Meeting
  • Fellowship Portal
  • Position Statements

© 2023 by the American Society of Neuroradiology | Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire