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Research ArticleBrain

Diffusion-Negative Stroke: A Report of Two Cases

Paul Y-K. Wang, Peter B. Barker, Robert J. Wityk, Aziz M. Uluğ, Peter C. M. van Zijl and Norman J. Beauchamp
American Journal of Neuroradiology November 1999, 20 (10) 1876-1880;
Paul Y-K. Wang
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Peter B. Barker
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Robert J. Wityk
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Aziz M. Uluğ
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Peter C. M. van Zijl
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Norman J. Beauchamp Jr
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Abstract

Summary: Diffusion-weighted MR imaging is generally thought to be highly sensitive for the diagnosis of acute stroke. We report two cases of hyperacute stroke with absence of changes on diffusion-weighted images within 4 hours of symptom onset. Follow-up studies, performed 4 days later, showed infarction in regions compatible with the clinical presentation and (in one case) with the initial perfusion deficit. These cases indicate that normal findings on diffusion-weighted images in patients with suspected cerebral ischemia do not rule out impending infarction.

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American Journal of Neuroradiology
Vol. 20, Issue 10
1 Nov 1999
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Diffusion-Negative Stroke: A Report of Two Cases
Paul Y-K. Wang, Peter B. Barker, Robert J. Wityk, Aziz M. Uluğ, Peter C. M. van Zijl, Norman J. Beauchamp
American Journal of Neuroradiology Nov 1999, 20 (10) 1876-1880;

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Diffusion-Negative Stroke: A Report of Two Cases
Paul Y-K. Wang, Peter B. Barker, Robert J. Wityk, Aziz M. Uluğ, Peter C. M. van Zijl, Norman J. Beauchamp
American Journal of Neuroradiology Nov 1999, 20 (10) 1876-1880;
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Cited By...

  • Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association
  • Ischemic Cerebral Damage: An Appraisal of Synaptic Failure
  • Recommendations for Imaging of Acute Ischemic Stroke: A Scientific Statement From the American Heart Association
  • The clinical significance of diffusion-weighted MR imaging in infratentorial strokes
  • Guidelines and Recommendations for Perfusion Imaging in Cerebral Ischemia: A Scientific Statement for Healthcare Professionals by the Writing Group on Perfusion Imaging, From the Council on Cardiovascular Radiology of the American Heart Association
  • Quantification of Perfusion Using Bolus Tracking Magnetic Resonance Imaging in Stroke: Assumptions, Limitations, and Potential Implications for Clinical Use
  • Benefits of Perfusion MR Imaging Relative to Diffusion MR Imaging in the Diagnosis and Treatment of Hyperacute Stroke
  • Arterial Hyperintensity on Fast Fluid-attenuated Inversion Recovery Images: A Subtle Finding for Hyperacute Stroke Undetected by Diffusion-weighted MR Imaging
  • Systematic Review of Diffusion and Perfusion Imaging in Acute Ischemic Stroke
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