Research ArticlePEDIATRICS
Sonography, CT, and MR Imaging: A Prospective Comparison of Neonates with Suspected Intracranial Ischemia and Hemorrhage
Francis G. Blankenberg, Nyu-Nyu Loh, Paige Bracci, Helen E. D'Arceuil, William D. Rhine, Alexander M. Norbash, Barton Lane, Angela Berg, Brenda Person, Michelle Coutant and Dieter R. Enzmann
American Journal of Neuroradiology January 2000, 21 (1) 213-218;
Francis G. Blankenberg
aFrom the Department of Radiology (F.G.B., N.-N.L., H.E.D., A.M.N., B.L., D.R.E.), Stanford University School of Medicine, Stanford, the Department of Epidemiology and Biostatistics (P.B.), Cancer Epidemiology Studies, San Francisco, and the Departments of Pediatrics, Neonatal Medicine (W.D.R.) and Pediatric Radiology (A.B., B.P., M.C.), Lucile Salter Packard Children's Hospital, Palo Alto, CA.
Nyu-Nyu Loh
aFrom the Department of Radiology (F.G.B., N.-N.L., H.E.D., A.M.N., B.L., D.R.E.), Stanford University School of Medicine, Stanford, the Department of Epidemiology and Biostatistics (P.B.), Cancer Epidemiology Studies, San Francisco, and the Departments of Pediatrics, Neonatal Medicine (W.D.R.) and Pediatric Radiology (A.B., B.P., M.C.), Lucile Salter Packard Children's Hospital, Palo Alto, CA.
Paige Bracci
aFrom the Department of Radiology (F.G.B., N.-N.L., H.E.D., A.M.N., B.L., D.R.E.), Stanford University School of Medicine, Stanford, the Department of Epidemiology and Biostatistics (P.B.), Cancer Epidemiology Studies, San Francisco, and the Departments of Pediatrics, Neonatal Medicine (W.D.R.) and Pediatric Radiology (A.B., B.P., M.C.), Lucile Salter Packard Children's Hospital, Palo Alto, CA.
Helen E. D'Arceuil
aFrom the Department of Radiology (F.G.B., N.-N.L., H.E.D., A.M.N., B.L., D.R.E.), Stanford University School of Medicine, Stanford, the Department of Epidemiology and Biostatistics (P.B.), Cancer Epidemiology Studies, San Francisco, and the Departments of Pediatrics, Neonatal Medicine (W.D.R.) and Pediatric Radiology (A.B., B.P., M.C.), Lucile Salter Packard Children's Hospital, Palo Alto, CA.
William D. Rhine
aFrom the Department of Radiology (F.G.B., N.-N.L., H.E.D., A.M.N., B.L., D.R.E.), Stanford University School of Medicine, Stanford, the Department of Epidemiology and Biostatistics (P.B.), Cancer Epidemiology Studies, San Francisco, and the Departments of Pediatrics, Neonatal Medicine (W.D.R.) and Pediatric Radiology (A.B., B.P., M.C.), Lucile Salter Packard Children's Hospital, Palo Alto, CA.
Alexander M. Norbash
aFrom the Department of Radiology (F.G.B., N.-N.L., H.E.D., A.M.N., B.L., D.R.E.), Stanford University School of Medicine, Stanford, the Department of Epidemiology and Biostatistics (P.B.), Cancer Epidemiology Studies, San Francisco, and the Departments of Pediatrics, Neonatal Medicine (W.D.R.) and Pediatric Radiology (A.B., B.P., M.C.), Lucile Salter Packard Children's Hospital, Palo Alto, CA.
Barton Lane
aFrom the Department of Radiology (F.G.B., N.-N.L., H.E.D., A.M.N., B.L., D.R.E.), Stanford University School of Medicine, Stanford, the Department of Epidemiology and Biostatistics (P.B.), Cancer Epidemiology Studies, San Francisco, and the Departments of Pediatrics, Neonatal Medicine (W.D.R.) and Pediatric Radiology (A.B., B.P., M.C.), Lucile Salter Packard Children's Hospital, Palo Alto, CA.
Angela Berg
aFrom the Department of Radiology (F.G.B., N.-N.L., H.E.D., A.M.N., B.L., D.R.E.), Stanford University School of Medicine, Stanford, the Department of Epidemiology and Biostatistics (P.B.), Cancer Epidemiology Studies, San Francisco, and the Departments of Pediatrics, Neonatal Medicine (W.D.R.) and Pediatric Radiology (A.B., B.P., M.C.), Lucile Salter Packard Children's Hospital, Palo Alto, CA.
Brenda Person
aFrom the Department of Radiology (F.G.B., N.-N.L., H.E.D., A.M.N., B.L., D.R.E.), Stanford University School of Medicine, Stanford, the Department of Epidemiology and Biostatistics (P.B.), Cancer Epidemiology Studies, San Francisco, and the Departments of Pediatrics, Neonatal Medicine (W.D.R.) and Pediatric Radiology (A.B., B.P., M.C.), Lucile Salter Packard Children's Hospital, Palo Alto, CA.
Michelle Coutant
aFrom the Department of Radiology (F.G.B., N.-N.L., H.E.D., A.M.N., B.L., D.R.E.), Stanford University School of Medicine, Stanford, the Department of Epidemiology and Biostatistics (P.B.), Cancer Epidemiology Studies, San Francisco, and the Departments of Pediatrics, Neonatal Medicine (W.D.R.) and Pediatric Radiology (A.B., B.P., M.C.), Lucile Salter Packard Children's Hospital, Palo Alto, CA.
Dieter R. Enzmann
aFrom the Department of Radiology (F.G.B., N.-N.L., H.E.D., A.M.N., B.L., D.R.E.), Stanford University School of Medicine, Stanford, the Department of Epidemiology and Biostatistics (P.B.), Cancer Epidemiology Studies, San Francisco, and the Departments of Pediatrics, Neonatal Medicine (W.D.R.) and Pediatric Radiology (A.B., B.P., M.C.), Lucile Salter Packard Children's Hospital, Palo Alto, CA.

References
- Enzmann D, Murphy-Irwin K, Stevenson D, Ariagno R, Barton J, Sunshine P. The natural history of subependymal germinal matrix hemorrhage. Am J Perinatol 1985;2:123-133
- Hay CT, Rumack CM, Horgan JG. Cranial sonography: intracranial hemorrhage, periventricular leukomalacia, and asphyxia. Clin Diagn Ultrasound 1989;24:25-42
- Cohen HL, Haller JO. Advances in perinatal neurosonography. AJR Am J Radiol 1994;163:801-810
- Matamoros A, Anderson JC, Mc Connell J, Bolam DL. Neurosonographic findings in infants treated with extracorporeal membrane oxygenation (ECMO). J Child Neurol 1989;4(suppl):52-61
- Babcock DS, Matsumoto JS. Update on cranial sonography of the infant. In: Rifkin MD, Charboneau JW, Laing FC, eds. Syllabus: A Special Course in Ultrasound 1991. Oak Brook: Radiological Society of North America; 1991:337-345
- von Allmen D, Babcock D, Matsumoto J, et al. The predictive value of head ultrasound in the ECMO candidate. J Pediatr Surg 1992;27:36-39
- Keeney SE, Adcock EW, McArdle CB. Prospective observation of 100 high-risk neonates by high-field (1.5 Tesla) magnetic resonance imaging of the central nervous system: I: intraventricular and extracerebral lesions. Pediatrics 1991;87:421-430
- Keeney SE, Adcock EW, McArdle CB. Prospective observation of 100 high-risk neonates by high-field (1.5 Tesla) magnetic resonance imaging of the central nervous system: II: lesions associated with hypoxic-ischemic encephalopathy. Pediatrics 1991;87:431-438
- Byrne P, Welch R, Johnson MA, Darrah J, Piper M. Serial magnetic resonance imaging in neonatal hypoxic-ischemic encephalopathy. J Pediatr 1990;117:694-700
- ↵
- Pinto-Martin JA, Riolo S, Cnaan A, Holzman C, Susser MW, Paneth N. Cranial ultrasound prediction of disabling and nondisabling cerebral palsy at age two in a low birth weight population. Pediatrics 1995;95:249-254
- Bulas DL, Glass P, O'Donnell RM, Taylor GA, Short BL, Verzina GL. Neonates treated with ECMO: Predictive value of CT and US neuroimaging findings on short-term neurodevelopmental outcome. Radiology 1995;195:407-412
- Aziz K, Vickar DB, Sauve RS, Etches PC, Pain KS, Robertson CMT. Province-based study of neurologic disability of children weighing 500 through 1249 grams at birth in relation to neonatal cerebral ultrasound findings. Pediatrics 1995;95:837-844
- Boal DKB, Watterberg KL, Miles S, Gifford KL. Optimal cost-effective timing of cranial ultrasound screening in low-birth-weight infants. Pediatri Radiol 1995;25:425-428
- ↵Blankenberg FG, Norbash AM, Barton L, Stevenson DK, Bracci PM, Enzmann DR. Neonatal intracranial ischemia and hemorrhage: diagnosis with US, CT and MR imaging. Radiology 1996;199:253-259
- Barkovich JA, Westmark K, Partridge C, Sola A, Ferriero DM. Perinatal asphyxia: MR findings in the first 10 days. AJNR Am J of Neuroradiol 1995;16:427-438
- Bulas DL, Taylor GA, O'Donnell RM, Short BL, Fitz CR, Vezina G. Intracranial abnormalities in infants treated with extracorporeal membrane oxygenation: update on sonographic and CT findings. AJNR Am J Neuroradiol 1996;17:287-294
- ↵van de Bor M, den Ouden L, Guit GL. Value of cranial ultrasound and magnetic resonance imaging in predicting neurodevelopmental outcome in preterm infants. Pediatrics 1992;90:196-199
- Skranes JS, Vik T, Nilsen G, et al. Cerebral magnetic resonance imaging (MRI) and mental and motor function of very low birth weight infants at one year of corrected age. Neuropediatrics 1993;24:256-262
- Scher MS, Belfar H, Martin J, Painter MJ. Destructive brain lesions of presumed fetal onset: antepartum causes of cerebral palsy. Pediatrics 1991;88:898-906
- Allan WC, Riviello JJ. Perinatal cerebrovascular disease in the neonate: parenchymal ischemic lesions in term and preterm infants. Pediatr Clin North Am 1992;39:621-650
- Menkes JH, Curran J. Clinical and MR correlates in children with extra pyramidal cerebral palsy. AJNR Am J Neuroradiol 1994;15:451-457
- Ford LM, Steichen J, Steichen Asch PA, Babcock D, Fogelson MH. Neurologic status and intracranial hemorrhage in very-low-birth-weight preterm infants. AJDC 1989;143:1186-1190
- ↵Papile LA, Burnstein J, Burnstein R, Koffler H. Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants less than 1500 gm. J Pediatr 1978;92:529-534
- ↵Fleiss JL. Statistical Method for Rates and Proportions. 2nd ed. New York: Wiley; 1981;
- ↵
- Blankenberg FG, Loh N-N, Norbash AM, et al. Impaired cerebrovascular autoregulation after hypoxic-ischemic injury in extremely low-birth-weight neonates: detection with power and pulsed wave Doppler US. Radiology 1997;205:563-568
- Azzarelli B, Caldemeyer KS, Phillips JP, DeMyer WE. Hypoxic-ischemic encephalopathy in areas of primary myelination: a neuroimaging and PET study. Pediatr Neurol 1996;14:108-116
- Volpe JS, Herscovitch P, Perlman JM, Raichle ME. Position emission tomography in the newborn: Extensive impairment of regional blood flow with intraventricular hemorrhage and hemorrhagic intracerebral involvement. Pediatrics 1983;72:589-601
- Mountz JM, Deutsch G, Khan SH. Regional cerebral blood flow changes in stroke imaged by Tc-99m HMPAO SPECT with corresponding anatomic image comparison. Clin Nucl Med 1993;18:1067-1082
- Martin E, Buchli R, Ritter S, et al. Diagnostic and prognostic value of cerebral 31P magnetic resonance spectroscopy in neonates with perinatal asphyxia. Pediatr Res 1996;40:749-758
- Cowan FM, Pennock JM, Hanrahan JD, Manji KP, Edwards AD. Early detection of cerebral infarction and hypoxic ischemic encephalopathy in neonates using diffusion-weighted magnetic resonance imaging. Neuropediatrics 1994;25:172-175
- Taylor GA, Short BL, Walker LK, Traystman RJ. Intracranial blood flow: quantification with duplex Doppler color doppler flow US. Radiology 1990;176:231-236
- Taylor GA, Trescher WA, Traystman RJ, Johnston MV. Acute experimental neuronal injury in the newborn lamb: US characterization and demonstration of hemodynamic effects. Pediatr Radiol 1993;23:268-275
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Sonography, CT, and MR Imaging: A Prospective Comparison of Neonates with Suspected Intracranial Ischemia and Hemorrhage
Francis G. Blankenberg, Nyu-Nyu Loh, Paige Bracci, Helen E. D'Arceuil, William D. Rhine, Alexander M. Norbash, Barton Lane, Angela Berg, Brenda Person, Michelle Coutant, Dieter R. Enzmann
American Journal of Neuroradiology Jan 2000, 21 (1) 213-218;
Sonography, CT, and MR Imaging: A Prospective Comparison of Neonates with Suspected Intracranial Ischemia and Hemorrhage
Francis G. Blankenberg, Nyu-Nyu Loh, Paige Bracci, Helen E. D'Arceuil, William D. Rhine, Alexander M. Norbash, Barton Lane, Angela Berg, Brenda Person, Michelle Coutant, Dieter R. Enzmann
American Journal of Neuroradiology Jan 2000, 21 (1) 213-218;
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