Article Figures & Data
Figures
- Fig 1.
CT sections of a tonsil carcinoma on pre- and posttreatment CT scans. The carcinoma is necrotic on the pretreatment scan. This is also a subtle lesion (difficulty rating = 4 for the posttreatment scan) in the dataset. A and B, An axial section on the pretreatment scan (A), the automatic segmentation (white contour, B), and the reference-standard (hand-drawn) segmentation (black contour, B) superimposed on the pretreatment scan. C and D, An axial section on the posttreatment scan (C), the automatic segmentation (white contour, D), and the reference-standard segmentation (black contour, D) superimposed on the posttreatment scan. The radiologist's hand-drawn bounding box (white rectangle) used for the automatic segmentation is also shown in B and D. The lesion is shown on the best section marked by the radiologist for each scan.
- Fig 2.
CT sections of a heterogeneous tongue carcinoma on pre- and posttreatment CT scans. This lesion has a difficulty rating of 2. A and B, An axial section on the pretreatment scan (A), the automatic segmentation (white contour, B), and the reference-standard (hand-drawn) segmentation (black contour, B) superimposed on the pretreatment scan. C and D, An axial section on the posttreatment scan (C), the automatic segmentation (white contour, D), and the reference standard segmentation (black contour, D) superimposed on the posttreatment scan. The radiologist's hand-drawn bounding box (white rectangle) used for the automatic segmentation is also shown in B and D. The lesion is shown on the best section marked by the radiologist for each scan.
- Fig 3.
Automatic-versus-manual estimates of the pretreatment volumes for the 34 primary-site tumors (correlation ICC = 0.98). A, Scatterplot. B, Bland-Altman plot. The solid line is the mean; the dashed line is ±2 SDs.
- Fig 4.
Automatic-versus-manual estimates of the posttreatment volumes for the 34 primary-site tumors (correlation ICC = 0.98). A, Scatterplot. B, Bland-Altman plot. The solid line is the mean; the dashed line is ±2 SDs.
- Fig 5.
Automatic-versus-manual estimates of the pre- to posttreatment volume change for the 34 primary-site tumors (correlation ICC = 0.95). A, Scatterplot. B, Bland-Altman plot. The solid line is the mean; the dashed line is ±2 SDs.
- Fig 6.
Automatic-versus-manual estimates of the percentage pre- to posttreatment volume change for the 34 primary-site tumors (correlation ICC = 0.95). A, Scatterplot. B, Bland-Altman plot. The solid line is the mean; the dashed line is ±2 SDs.
Tables
- Table 1:
The average signed errors and average absolute errors of the automatic estimate of the percentage pre- to posttreatment volume change for the 34 primary tumors based on reading 1 and reading 2 bounding boxes
Tumor Type Number of Tumors Average Difficulty (mean, range) Reading 1 Reading 2 Signed Error (%)a Absolute Error (%)a Signed Error (%)a Absolute Error (%)a Tongue 10 3.4, 2–5 −2.5 ± 6.9 5.6 ± 4.4 1.8 ± 10.0 7.9 ± 6.0 Tonsil 2 4, 3–5 −0.2 ± 5.5 3.9 ± 0.3 −0.4 ± 14.1 10.0 ± 0.6 Vallecular 2 3.5, 2–5 −5.1 ± 0.2 5.1 ± 0.2 −8.3 ± 0.4 8.3 ± 0.4 Supraglottic 14 2, 1–3 −0.9 ± 8.0 5.7 ± 5.5 −5.4 ± 13.1 10.8 ± 8.8 Epiglottic 5 2.2, 1–3 −2.8 ± 13.6 9.2 ± 9.4 −3.6 ± 8.0 7.5 ± 3.1 Hard palate 1 3 −20.0 ± 0 20.0 ± 0 −18.9 ± 0 18.9 ± 0 Total 34 −2.4 ± 8.5 6.4 ± 5.9 −3.3 ± 11.3 9.5 ± 6.8 -
a Mean.
-
Radiologist Automatic Pretreatment Posttreatment Pretreatment Posttreatment Average 14.5 6.7 15.9 7.7 Range 2.1–55.4 0.4–42.0 2.2–61.3 0.6–45.1 -
a The estimated volumes (cubic centimeters) are based on the radiologists' outlined contours.
-
- Table 3:
The average difference of box size between reading 1 and reading 2 in x-, y-, and z-dimensions
Difference of the Box Size in Dimension Signed Difference (%) Absolute Difference (%) X 0.0 ± 21.2 16.0 ± 13.7 Y −2.1 ± 27.6 17.5 ± 21.3 Z −14.1 ± 26.6 20.0 ± 22.4 - Table 4:
Correlation between the automatic estimates obtained from the reading 1 and reading 2 bounding boxes for the 34 primary site tumors
ICC P Valuea Pretreatment volume 0.92 .58 Posttreatment volume 0.88 .86 Pre- to posttreatment change 0.89 .29 % Pre- to posttreatment change 0.90 .67 -
a Paired Student t test estimation.
-
- Table 5:
The average signed errors and average absolute errors of the automatic estimate of the percentage pre- to posttreatment volume change of the necrotic and non-necrotic primary tumors based on reading 1 and reading 2 bounding boxes
Tumor Type No. Tumors Reading 1 Reading 2 Signed Error (%)a Absolute Error (%)a Signed Error (%)a Absolute Error (%)a Necrotic tumors 10 −2.5 ± 10.6 7.3 ± 9.6 −0.8 ± 10.1 8.3 ± 4.8 Non-necrotic tumors 24 −2.4 ± 7.7 6.1 ± 5.1 −4.4 ± 11.1 10.0 ± 7.4 P valueb 0.97 0.61 0.41 0.52 -
a Mean.
-
b Student t test estimation.
-
