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Review ArticleReview Articles
Open Access

Pseudotumor Cerebri: Brief Review of Clinical Syndrome and Imaging Findings

A.J. Degnan and L.M. Levy
American Journal of Neuroradiology December 2011, 32 (11) 1986-1993; DOI: https://doi.org/10.3174/ajnr.A2404
A.J. Degnan
aFrom the Department of Radiology, George Washington University Hospital, Washington, DC.
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L.M. Levy
aFrom the Department of Radiology, George Washington University Hospital, Washington, DC.
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Abstract

PTC is a clinical entity of uncertain etiology characterized by intracranial hypertension. The syndrome classically manifests with headaches and visual changes in women with obesity. Traditionally, imaging ruled out secondary causes of elevated CSF pressure but now may reveal findings frequently seen in patients with PTC, including the following: flattening of the globe, an empty sella, an enlarged ONS, protrusion and enhancement of the optic nerve head, and increased tortuosity of the optic nerve. Novel imaging methods, including MR venography, have additionally identified sinovenous stenosis as a potential indicator of PTC.

ABBREVIATIONS

BMI
body-mass index
CN
cranial nerve
HIV
human immunodeficiency virus
ICP
intracranial pressure
IIH
idiopathic intracranial hypertension
ISF
interstitial fluid
MRI
MR imaging
ONS
optic nerve sheath
ONSF
optic nerve sheath fenestration
IOP
intraocular pressure
PCOS
polycystic ovary syndrome
PTC
pseudotumor cerebri syndrome
  • © 2011 by American Journal of Neuroradiology

Indicates open access to non-subscribers at www.ajnr.org

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American Journal of Neuroradiology: 32 (11)
American Journal of Neuroradiology
Vol. 32, Issue 11
1 Dec 2011
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Pseudotumor Cerebri: Brief Review of Clinical Syndrome and Imaging Findings
A.J. Degnan, L.M. Levy
American Journal of Neuroradiology Dec 2011, 32 (11) 1986-1993; DOI: 10.3174/ajnr.A2404

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Pseudotumor Cerebri: Brief Review of Clinical Syndrome and Imaging Findings
A.J. Degnan, L.M. Levy
American Journal of Neuroradiology Dec 2011, 32 (11) 1986-1993; DOI: 10.3174/ajnr.A2404
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  • Empty Sella Is a Sign of Symptomatic Lateral Sinus Stenosis and Not Intracranial Hypertension
  • Mastoid osteoma with stenosis of transverse and sigmoid sinuses as a cause of pseudotumor cerebri
  • The Occipital Emissary Vein: A Possible Marker for Pseudotumor Cerebri
  • Contrast-Enhanced 3D-FLAIR Imaging of the Optic Nerve and Optic Nerve Head: Novel Neuroimaging Findings of Idiopathic Intracranial Hypertension
  • Idiopathic intracranial hypertension: consensus guidelines on management
  • A new index for the assessment of transverse sinus stenosis for diagnosing idiopathic intracranial hypertension
  • Quantifying the Cerebral Hemodynamics of Dural Arteriovenous Fistula in Transverse Sigmoid Sinus Complicated by Sinus Stenosis: A Retrospective Cohort Study
  • Obesity in Children and Adolescents: Health Effects and Imaging Implications
  • Structural Brain Changes following Long-Term 6{degrees} Head-Down Tilt Bed Rest as an Analog for Spaceflight
  • Meta-Analysis of CSF Diversion Procedures and Dural Venous Sinus Stenting in the Setting of Medically Refractory Idiopathic Intracranial Hypertension
  • Volumetric Assessment of Optic Nerve Sheath and Hypophysis in Idiopathic Intracranial Hypertension
  • MR Imaging of Papilledema and Visual Pathways: Effects of Increased Intracranial Pressure and Pathophysiologic Mechanisms
  • Magnetic resonance imaging of CNS in 15 043 children with GH deficiency in KIGS (Pfizer International Growth Database)
  • MRI Evidence of Impaired CSF Homeostasis in Obesity-Associated Idiopathic Intracranial Hypertension
  • Update on the pathophysiology and management of idiopathic intracranial hypertension
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