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Research ArticlePediatricsC

Hydrocephalus in Patients with Neurofibromatosis Type 1: MR Imaging Findings and the Outcome of Endoscopic Third Ventriculostomy

A. Dinçer, U. Yener and M.M. Özek
American Journal of Neuroradiology April 2011, 32 (4) 643-646; DOI: https://doi.org/10.3174/ajnr.A2357
A. Dinçer
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U. Yener
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M.M. Özek
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Abstract

SUMMARY: Although hydrocephalus associated with NF-1 is not rare, up to now the MR imaging findings in these patients and the role of ETV in the treatment of hydrocephalus associated with NF-1 have not been investigated thoroughly. We present the MR imaging findings of hydrocephalus associated with NF-1 in 7 of 54 patients with NF-1. Although the types of obstruction were various, including aqueductal web, superior velum medullary synechia, periaqueductal/tectal hamartomas, cerebellar and pontine tegmentum hamartomas, brain stem glioma, or a combination, the presence of hamartomas was a consistent finding in patients with NF-1 with hydrocephalus. In 5 cases, 8 ETV procedures were performed and followed for up to 53 months. All children treated with ETV were shunt-free at their most recent examinations. ETV may be the primary procedure for the treatment of hydrocephalus associated with NF-1, regardless of the cause and the level of the obstruction.

Abbreviations

cine PC
cine phase-contrast
CNS
central nervous system
ETV
endoscopic third ventriculostomy
3D-CISS
3D constructive interference in steady state
NF-1
neurofibromatosis type 1
TSE
turbo spin-echo
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American Journal of Neuroradiology: 32 (4)
American Journal of Neuroradiology
Vol. 32, Issue 4
1 Apr 2011
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Hydrocephalus in Patients with Neurofibromatosis Type 1: MR Imaging Findings and the Outcome of Endoscopic Third Ventriculostomy
A. Dinçer, U. Yener, M.M. Özek
American Journal of Neuroradiology Apr 2011, 32 (4) 643-646; DOI: 10.3174/ajnr.A2357

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Hydrocephalus in Patients with Neurofibromatosis Type 1: MR Imaging Findings and the Outcome of Endoscopic Third Ventriculostomy
A. Dinçer, U. Yener, M.M. Özek
American Journal of Neuroradiology Apr 2011, 32 (4) 643-646; DOI: 10.3174/ajnr.A2357
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