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Author (year) Study Design No. of Patients with AcomA Aneurysms AcomA Aneurysms Treated Patients with Ruptured AcomA Aneurysms Patients with Unruptured AcomA Aneurysms Birknes et al (2006) Retrospective 123 123 113 10 Cherian et al (2001) Prospective 103 103 103 0 Choi et al (2011) Retrospective 45 45 45 0 Elias et al (2003) Prospective 30 30 30 0 Finitsis et al (2010) Prospective 280 281 239 42 Guglielmi et al (2009) Retrospective 306 306 236 70 Huang et al (2011) Retrospective 20 20 20 0 Johnson et al (2012) Retrospective 64 64 – – Leclerc et al (2002) Prospective 20 20 20 0 Moret et al (1996) Prospective 36 36 30 6 Proust et al (2003) Prospective 37 37 36 1 Raslan et al (2011) Retrospective 44 44 43 1 Schuette et al (2011) Retrospective 347 347 277 70 Songsaeng et al (2010) Retrospective 96 96 7 89 Note:—Studies are from References 10–13 and 15–24. AcomA indicates anterior communicating artery.
Outcome No. of Studies Raw No. of Events in All Aneurysmsa Meta-Analysis Percentage (95% CI) I2 Intraoperative rupture 11 57/1387 4% (3–6%) 0 Vasospasm 6 182/1091 13% (5–28%) 95 Re-bleeding event 11 16/1065 2% (1–4%) 0 Aneurysm retreatment 10 73/777 7% (5–12%) 60 Morbidity or mortality due to stroke <30 days 10 21/771 3% (2–6%) 32 Permanent procedure-related morbidity 11 53/1077 6% (4–8%) 47 Procedure-related mortality 11 25/1077 3% (2–4%) 15 ↵a Discordances between the raw event percentages and the percentages calculated from the meta-analysis are caused by greater weights assigned to outcomes of studies with larger sample sizes.
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