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Tables
Aneurysm Characteristics Anterior ICA ≥10 mm (n = 311) Anterior <10 mm (n = 349) Posterior (n = 59) Other Anterior ≥10 mm (n = 178) Total (n = 896)a P Value Aneurysm size (mm) Mean ± SD 16.8 ± 6.2 5.2 ± 2.2 14.5 ± 9.0 9.8 ± 7.9 10.7 ± 7.7 <.001 Median, range 15.0, 10.0–42.0 5.0, 1.0–9.9 11.8, 1.7–45.0 7.2, 1.0–55.0 9.0, 1.0–55.0 Aneurysm type Small 0 349/349 (100%) 19/58 (32.8%) 105/178 (59.0%) 473/897 (52.8%) Large 268/311 (86.2%) 0 29/58 (50.0%) 60/178 (33.7%) 357/897 (39.8%) Giant 43/311 (13.8%) 0 10/58 (17.2%) 13/178 (7.3%) 66/897 (7.3%) Aneurysm neck (mm) Mean ± SD 8.5 ± 5.1 4.1 ± 2.2 9.3 ± 8.4 5.3 ± 5.1 6.2 + 4.9 <.001 Median, range 7.6, 0.9–50.0 4.0, 0.8–22.0 8.0, 1.7–53.0 4.0, 1.0–50.0 5.0, 0.8–53.0 Aneurysm shape Fusiform 49/311 (15.8%) 17/349 (4.9%) 17/59 (28.8%) 29/178 (16.3%) 112/897 (12.5%) <.001 Saccular 239/311 (76.9%) 305/349 (87.4%) 25/59 (42.4%) 118/178 (66.3%) 686/897 (76.5%) Dissecting 10/311 (3.2%) 8/349 (2.3%) 13/59 (22.0%) 22/178 (12.4%) 53/897 (5.9%) Other 13/311 (4.2%) 19/349 (5.4%) 4/59 (6.8%) 9/178 (5.1%) 46/897 (5.1%) Aneurysm location Internal carotid artery 311/311 (100%) 349/349 (100%) 0 0 660/897 (73.6%) <.001 Middle cerebral artery 0 0 0 43/178 (24.2%) 43/897 (4.8%) Posterior cerebral artery 0 0 15/59 (25.4%) 0 15/897 (1.7%) Basilar artery 0 0 44/59 (74.6%) 0 44/897 (4.9%) Other 0 0 0 135/178 (75.8%) 135/897 (15.1%) Presented with ruptured aneurysm 12/311 (3.9%) 24/345 (7.0%) 4/59 (6.8%) 34/176 (19.3%) 74/891 (8.2%) <.001 Multiple PEDs used 143/311 (46.0%) 97/347 (28.0%) 19/59 (32.2%) 47/178 (26.4%) 306/895 (34.2%) <.001 Note:—n indicates the number of aneurysms.
↵a Aneurysm size was not reported for 10 aneurysms.
Complications Anterior ICA ≥10 mm (n = 275) Anterior ICA <10 mm (n = 294) Posterior (n = 55) Other Anterior (n = 165) Total (n = 793)a 95% CI; P Value Mean aneurysm size (mm) 16.8 ± 6.2 5.2 ± 2.2 14.5 ± 9.0 9.8 ± 7.9 10.7 ± 7.7 (10.2–11.2); <.001 Spontaneous rupture 4 (0.7%) 0 (0.0%) 0 (0.0%) 1 (0.6%) 5 (0.6%) (0.2%–1.5%); .17 Intraparenchymal hemorrhage 6 (2.2%) 6 (2.0%) 1 (1.8%) 6 (3.6%) 19 (2.4%) (1.3%–3.4%); .73 Ischemic stroke 15 (5.5%) 8 (2.7%) 4 (7.3%) 10 (6.1%) 37 (4.7%) (3.2%–6.2%); .16 Parent artery stenosis 1 (0.4%) 1 (0.4%) 0 (0.0%) 0 (0.0%) 2 (0.3%) (0%–0.7%); 1.0 Cranial neuropathy 2 (0.7%) 0 (0.0%) 0 (0.0%) 0 (0.0%) 2 (0.3%) (0%–0.7%); .30 Neurologic morbidity 24 (8.7%) 14 (4.5%) 5 (9.1%) 16 (9.7%) 59 (7.4%) (5.6%–9.2%); .16 Neurologic mortality 11 (4.0%) 4 (1.4%) 6 (10.9%) 9 (5.5%) 30 (3.8%) (2.5%–5.1%); <.01 Neurologic morbidity and mortality (all patients) 26 (9.5%) 14 (4.8%) 9 (16.4%) 18 (10.9%) 67 (8.4%) (6.5%–10.3%); .01 Neurologic morbidity and mortality (patients with unruptured aneurysms) 24/263 (9.2%) 11/270 (4.1%) 7/51 (13.7%) 11/131 (8.4%) 53/717 (7.4%) (5.5%–9.3%); .03 Neurologic morbidity and mortality (patients with ruptured aneurysms) 2/12 (16.7%) 3/24 (12.5%) 2/4 (50.0%) 7/34 (20.6%) 14/76 (18.4%) (10.0%–27.1%); .35 Neurologic morbidity and mortality (excluding ruptured, dissecting, or fusiform aneurysms) 15 (7.0%) 9 (3.6%) 3 (12.0%) 6 (6.8%) 33 (5.7%) (4.1%–7.3%); .19 Note:—n indicates the number of patients.
↵a Numbers do not sum across categories and subcategories because some patients experienced >1 event.
Complications <72 Hours 72 Hours–30 Days >30 Days Total (n = 793)a P Value Anterior (n = 738) Posterior (n = 55) Anterior (n = 738) Posterior (n = 55) Anterior (n = 738) Posterior (n = 55) Spontaneous rupture 1 (0.1%) 0 (0%) 3 (0.4%) 0 (0%) 1 (0.1%) 0 (0%) 5 (0.6%) .51 Intraparenchymal hemorrhage 3 (0.4%) 1 (1.8%) 11 (1.5%) 0 (0%) 4 (0.5%) 0 (0%) 19 (2.4%) .83 Ischemic stroke 17 (2.3%) 2 (3.6%) 7 (0.9%) 0 (0%) 9 (1.2%) 2 (3.6%) 37 (4.7%) .58 Parent artery stenosis 0 (0%) 0 (0%) 1 (0.1%) 0 (0%) 1 (0.1%) 0 (0%) 2 (0.3%) .63 Cranial neuropathy 0 (0%) 0 (0%) 2 (0.3%) 0 (0%) 0 (0%) 0 (0%) 2 (0.3%) .58 Neurologic morbidity 20 (2.7%) 3 (5.5%) 21 (2.8%) 0 (0%) 13 (1.8%) 2 (3.6%) 59 (7.4%) .56 Neurologic mortality 4 (0.5%) 1 (1.8%) 13 (1.8%) 2 (3.6%) 7 (0.9%) 3 (5.5%) 30 (3.8%) <.01 Neurologic morbidity and mortality (all patients) 23 (3.1%) 3 (5.5%) 22 (3.0%) 2 (3.6%) 13 (1.8%) 4 (7.3%) 67 (8.4%) <.01 Neurologic morbidity and mortality (patients with unruptured aneurysms) 19/664 (2.9%) 3/51 (5.9%) 16/664 (2.4%) 1/51 (2.0%) 11/664 (1.7%) 3/51 (5.9%) 53/717 (7.4%) .08 Neurologic morbidity and mortality (patients with ruptured aneurysms) 4/70 (5.7%) 0/4 (0%) 6/70 (8.6%) 1/4 (25.0%) 2/70 (2.9%) 1/4 (25.0%) 14/76 (18.4%) .17 Neurologic morbidity and mortality (excluding ruptured, dissecting, or fusiform aneurysms) 13/549 (2.4%) 1/25 (4.0%) 12/549 (2.2%) 0/25 (0%) 5/549 (0.9%) 2/25 (8.0%) 33/575 (5.7%) .41 Note:—n indicates the number of patients.
↵a Numbers do not sum across categories and subcategories because some patients experienced >1 event.
Complications Small (n = 386) (N = 473) Large (n = 339) (N = 357) Giant (n = 62) (N = 66) Total (n = 793)a,b (N = 906) P Value Anterior (n = 372) Posterior (n = 14) Anterior (n = 309) Posterior (n = 30) Anterior (n = 52) Posterior (n = 10) Mean aneurysm size (mm) 5.1 ± 2.2 6.0 ± 2.6 14.8 ± 4.0 15.0 ± 4.3 28.8 ± 5.3 29.1 ± 7.2 10.7 ± 7.7 <.001 Spontaneous rupture 0 (0%) 0 (0%) 2 (0.5%) 0 (0%) 3 (5.8%) 0 (0%) 5 (0.6%) <.01 Intraparenchymal hemorrhage 7 (1.9%) 0 (0%) 8 (2.6%) 0 (0%) 3 (5.8%) 1 (10.0%) 19 (2.4%) .24 Ischemic stroke 10 (2.7%) 1 (7.1%) 16 (5.2%) 1 (3.3%) 7 (13.5%) 2 (20.0%) 37 (4.7%) <.01 Parent artery stenosis 1 (0.3%) 0 (0%) 1 (0.3%) 0 (0%) 0 (0%) 0 (0%) 2 (0.3%) 1.0 Cranial neuropathy 0 (0%) 0 (0%) 2 (0.6%) 0 (0%) 0 (0%) 0 (0%) 2 (0.3%) .41 Neurologic morbidity 18 (4.8%) 1 (7.1%) 24 (7.8%) 1 (3.3%) 12 (23.1%) 3 (30.0%) 59 (7.4%) <.01 Neurologic mortality 6 (1.6%) 1 (7.1%) 15 (4.9%) 2 (6.7%) 3 (5.8%) 3 (30.0%) 30 (3.8%) <.01 Neurologic morbidity and mortalitya (all patients) 19 (5.1%) 2 (14.3%) 27 (8.7%) 3 (10.0%) 12 (23.1%) 4 (40.0%) 67 (8.4%) <.01 Neurologic morbidity and mortality (patients with unruptured aneurysms) 11/321 (3.4%) 1/12 (8.3%) 23/291 (7.9%) 3/29 (10.3%) 12/51 (23.5%) 3/9 (33.3%) 53/717 (7.4%) <.01 Neurologic morbidity and mortality (patients with ruptured aneurysms) 8/51 (15.7%) 1/2 (50.0%) 4/18 (22.2%) 0/1 (0%) 0/1 (0%) 1/1 (100%) 14/76 (18.4%) .23 Neurologic morbidity and mortality (excluding ruptured, dissecting, or fusiform aneurysms) 11/294 (3.7%) 0/7 (0%) 12/217 (5.5%) 2/13 (15.4%) 7/37 (18.9%) 1/5 (20.0%) 33/574 (5.7%) <.01