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LetterLETTER

The Possible Role of Elastic Properties of the Brain and Optic Nerve Sheath in the Development of Spaceflight-Associated Neuro-Ocular Syndrome

P. Wostyn, T.H. Mader, C.R. Gibson, F.L. Wuyts, A. Van Ombergen, P. zu Eulenburg and P.P. De Deyn
American Journal of Neuroradiology March 2020, 41 (3) E14-E15; DOI: https://doi.org/10.3174/ajnr.A6430
P. Wostyn
aDepartment of PsychiatryPC Sint-AmandusBeernem, Belgium
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T.H. Mader
bColonel, US Army (retired), Moab, Utah
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C.R. Gibson
cCoastal Eye AssociatesWebster, TexasKBR, Houston, Texas
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F.L. Wuyts
dLab for Equilibrium Investigations and AerospaceUniversity of AntwerpAntwerp, Belgium
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A. Van Ombergen
eLab for Equilibrium Investigations and AerospaceDepartment of Translational NeurosciencesUniversity of AntwerpAntwerp, Belgium
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P. zu Eulenburg
fGerman Center for Vertigo and Balance Disorders Faculty of MedicineLudwig-Maximilians-University MunichMunich, Germany
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P.P. De Deyn
gDepartment of Biomedical Sciences Laboratory of Neurochemistry and BehaviorInstitute Born-BungeUniversity of AntwerpAntwerp, BelgiumDepartment of Neurology and Alzheimer Research CenterUniversity of Groningen and University Medical Center GroningenGroningen, the NetherlandsDepartment of Neurology and Memory ClinicMiddelheim General HospitalAntwerp, Belgium
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References

  1. 1.↵
    1. Roberts DR,
    2. Asemani D,
    3. Nietert PJ, et al
    . Prolonged microgravity affects human brain structure and function. AJNR Am J Neuroradiol 2019;40:1878–85 doi:10.3174/ajnr.A6249 pmid:31624117
    Abstract/FREE Full Text
  2. 2.↵
    1. Van Ombergen A,
    2. Jillings S,
    3. Jeurissen B, et al
    . Brain ventricular volume changes induced by long-duration spaceflight. Proc Natl Acad Sci USA 2019;116:10531–36 doi:10.1073/pnas.1820354116 pmid:31061119
    Abstract/FREE Full Text
  3. 3.↵
    1. Wostyn P,
    2. De Deyn PP
    . Intracranial pressure-induced optic nerve sheath response as a predictive biomarker for optic disc edema in astronauts. Biomark Med 2017;11:1003–08 doi:10.2217/bmm-2017-0218 pmid:28869392
    CrossRefPubMed
  4. 4.↵
    1. Wostyn P,
    2. De Deyn PP
    . Optic nerve sheath distention as a protective mechanism against the visual impairment and intracranial pressure syndrome in astronauts. Invest Ophthalmol Vis Sci 2017;58:4601–02 doi:10.1167/iovs.17-22600 pmid:28892828
    CrossRefPubMed
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American Journal of Neuroradiology: 41 (3)
American Journal of Neuroradiology
Vol. 41, Issue 3
1 Mar 2020
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The Possible Role of Elastic Properties of the Brain and Optic Nerve Sheath in the Development of Spaceflight-Associated Neuro-Ocular Syndrome
P. Wostyn, T.H. Mader, C.R. Gibson, F.L. Wuyts, A. Van Ombergen, P. zu Eulenburg, P.P. De Deyn
American Journal of Neuroradiology Mar 2020, 41 (3) E14-E15; DOI: 10.3174/ajnr.A6430

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The Possible Role of Elastic Properties of the Brain and Optic Nerve Sheath in the Development of Spaceflight-Associated Neuro-Ocular Syndrome
P. Wostyn, T.H. Mader, C.R. Gibson, F.L. Wuyts, A. Van Ombergen, P. zu Eulenburg, P.P. De Deyn
American Journal of Neuroradiology Mar 2020, 41 (3) E14-E15; DOI: 10.3174/ajnr.A6430
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  • Spaceflight associated neuro-ocular syndrome: proposed pathogenesis, terrestrial analogues, and emerging countermeasures
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  • Increased Ventricular Cerebrospinal Fluid Volumes in Spaceflight-Associated Neuroocular Syndrome—A Curse or a Blessing?
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  • Optic nerve sheath diameter and spaceflight: defining shortcomings and future directions
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  • Spaceflight Associated Neuro-Ocular Syndrome
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  • Spaceflight-Associated Neuro-ocular Syndrome (SANS): a review of proposed mechanisms and analogs
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    Expert Review of Ophthalmology 2020 15 4

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