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LetterLETTER

The Nosologic Term “Conversive” Disorder Should Be Abandoned

D. A. Lizarazo and A. Guarnizo
American Journal of Neuroradiology August 2022, 43 (8) E17; DOI: https://doi.org/10.3174/ajnr.A7504
D. A. Lizarazo
aFundación Santa Fe de BogotáUniversidad El BosqueBogotá, Colombia
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A. Guarnizo
aFundación Santa Fe de BogotáUniversidad El BosqueBogotá, Colombia
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We found the article by Prodi et al1 on the usefulness of a multimodal CT protocol in the diagnosis of stroke mimics very interesting. Among the pathologies evaluated is the so-called “conversive disorder,” a disorder in which diagnostic imaging was not useful.

The nosologic term “conversive disorder” should be abandoned, and instead the term “functional neurologic disorder” (FND) should be used. Recent research has made it clear that FND is not a rule-out diagnosis but a rule-in diagnosis based on positive physical examination findings.2 The term conversive disorder implies a psychiatric disease and leads the treating physician to think that there is no structural brain alteration; therefore, there should be no alteration in the diagnostic images. In recent years, it has been established that these patients do have subtle alterations on MR imaging,3⇓-5 such as smaller volume of the thalamus,5 an increased cortical thickening in the premotor cortex,3 and an inverse association between somatoform dissociation and left caudal anterior cingulate cortical thickness.4

The emergence of FND as a brain disease with an organic substrate and probable structural alterations should lead us to change the paradigm of the mental-versus-organic dichotomy.

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  • Disclosure forms provided by the authors are available with the full text and PDF of this article at www.ajnr.org.

References

  1. 1.↵
    1. Prodi E,
    2. Danieli L,
    3. Manno C, et al
    . Stroke mimics in the acute setting: role of multimodal CT protocol. AJNR Am J Neuroradiol 2022;43:216–22 doi:10.3174/ajnr.A7379 pmid:34969667
    Abstract/FREE Full Text
  2. 2.↵
    1. Aybek S,
    2. Perez DL
    . Diagnosis and management of functional neurological disorder. BMJ 2022;376:064 doi:10.1136/bmj.o64 pmid:35074803
    CrossRefPubMed
  3. 3.↵
    1. Aybek S,
    2. Nicholson TR,
    3. Draganski B, et al
    . Grey matter changes in motor conversion disorder. J Neurol Neurosurg Psychiatry 2014;85:236–38 doi:10.1136/jnnp-2012-304158 pmid:23236016
    Abstract/FREE Full Text
  4. 4.↵
    1. Perez DL,
    2. Matin N,
    3. Williams B, et al
    . Cortical thickness alterations linked to somatoform and psychological dissociation in functional neurological disorders. Hum Brain Mapp 2018;39:428–39 doi:10.1002/hbm.23853 pmid:29080235
    CrossRefPubMed
  5. 5.↵
    1. Nicholson TR,
    2. Aybek S,
    3. Kempton MJ, et al
    . A structural MRI study of motor conversion disorder: evidence of reduction in thalamic volume. J Neurol Neurosurg Psychiatry 2014;85:227–29 doi:10.1136/jnnp-2013-305012 pmid:24039028
    Abstract/FREE Full Text
  • © 2022 by American Journal of Neuroradiology
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American Journal of Neuroradiology: 43 (8)
American Journal of Neuroradiology
Vol. 43, Issue 8
1 Aug 2022
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The Nosologic Term “Conversive” Disorder Should Be Abandoned
D. A. Lizarazo, A. Guarnizo
American Journal of Neuroradiology Aug 2022, 43 (8) E17; DOI: 10.3174/ajnr.A7504

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The Nosologic Term “Conversive” Disorder Should Be Abandoned
D. A. Lizarazo, A. Guarnizo
American Journal of Neuroradiology Aug 2022, 43 (8) E17; DOI: 10.3174/ajnr.A7504
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