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Review ArticlePediatric Neuroimaging

An Atlas of Neonatal Neurovascular Imaging Anatomy as Depicted with Microvascular Imaging: The Intracranial Arteries

Shawn Lyo, Colbey W. Freeman, Santiago Martinez-Correa, Arastoo Vossough, Luis Octavio Tierradentro-García and Misun Hwang
American Journal of Neuroradiology October 2025, 46 (10) 1972-1984; DOI: https://doi.org/10.3174/ajnr.A8810
Shawn Lyo
aFrom the Department of Radiology (S.L., C.W.F., A.V., L.O.T.-G., M.H.), University of Pennsylvania Health System, Philadelphia, Pennsylvania
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  • ORCID record for Shawn Lyo
Colbey W. Freeman
aFrom the Department of Radiology (S.L., C.W.F., A.V., L.O.T.-G., M.H.), University of Pennsylvania Health System, Philadelphia, Pennsylvania
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Santiago Martinez-Correa
bDepartment of Radiology (S.M.-C., A.V., M.H.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
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  • ORCID record for Santiago Martinez-Correa
Arastoo Vossough
aFrom the Department of Radiology (S.L., C.W.F., A.V., L.O.T.-G., M.H.), University of Pennsylvania Health System, Philadelphia, Pennsylvania
bDepartment of Radiology (S.M.-C., A.V., M.H.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
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Luis Octavio Tierradentro-García
aFrom the Department of Radiology (S.L., C.W.F., A.V., L.O.T.-G., M.H.), University of Pennsylvania Health System, Philadelphia, Pennsylvania
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Misun Hwang
aFrom the Department of Radiology (S.L., C.W.F., A.V., L.O.T.-G., M.H.), University of Pennsylvania Health System, Philadelphia, Pennsylvania
bDepartment of Radiology (S.M.-C., A.V., M.H.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
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Abstract

SUMMARY: Neurosonography is an invaluable diagnostic tool for assessing the neonatal brain and typically includes grayscale and conventional Doppler imaging. Microvascular imaging (MVI) is an emerging imaging technique that offers promising potential in evaluating neonatal intracranial pathology. MVI allows for sensitive and detailed assessment of neurovascular anatomy that can be challenging to visualize with other imaging modalities. This enhanced visualization not only improves the reliability in identifying neurovascular landmarks but also allows more accurate identification and assessment of adjacent parenchymal and extra-axial structures. Our review aims to offer an atlas of neurovascular structures as visualized with MVI, intended as a reference for future research in this field. Here, we focus specifically on the appearance of the intracranial arterial circulation as seen on MVI.

ABBREVIATIONS:

ACA
anterior cerebral artery
AChoA
anterior choroidal artery
ACoA
anterior communicating artery
BA
basilar artery
CEUS
contrast-enhanced ultrasound
CN
cranial nerve
CPA
cerebellopontine angle
ILT
inferolateral trunk
MHT
meningohypophyseal trunk
MVI
microvascular imaging
PCA
posterior cerebral artery
PCoA
posterior communicating artery
SCA
superior cerebellar artery
  • © 2025 by American Journal of Neuroradiology
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American Journal of Neuroradiology: 46 (10)
American Journal of Neuroradiology
Vol. 46, Issue 10
1 Oct 2025
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Cite this article
Shawn Lyo, Colbey W. Freeman, Santiago Martinez-Correa, Arastoo Vossough, Luis Octavio Tierradentro-García, Misun Hwang
An Atlas of Neonatal Neurovascular Imaging Anatomy as Depicted with Microvascular Imaging: The Intracranial Arteries
American Journal of Neuroradiology Oct 2025, 46 (10) 1972-1984; DOI: 10.3174/ajnr.A8810

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Neonatal Cerebral Arterial Anatomy using MVI
Shawn Lyo, Colbey W. Freeman, Santiago Martinez-Correa, Arastoo Vossough, Luis Octavio Tierradentro-García, Misun Hwang
American Journal of Neuroradiology Oct 2025, 46 (10) 1972-1984; DOI: 10.3174/ajnr.A8810
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    • INTRACRANIAL ARTERIAL CIRCULATION
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