More articles from Brain

Brain tumor location has prognostic implications so these authors explored whether location also correlated with p53 status in 182 patients. Tumors occurring in the left medial temporal and right anterior temporal lobes were associated with high expression of mutant p53 and had significantly worse progression-free survival.

Because codeine is a popular drug and results in cognitive deficits, the authors assessed 30 chronic users and 30 controls with DTI. Chronic codeine users showed lower fractional anisotropy in 4 brain regions and higher scores on the Barratt Impulsiveness Scale. It appears that chronic codeine-containing syrup abuse may be associated with disruptions in brain white matter integrity and that these microstructural deficits may be linked to higher impulsivity in chronic users.