More articles from FUNCTIONAL
- Cerebral Blood Flow Improvement after Indirect Revascularization for Pediatric Moyamoya Disease: A Statistical Analysis of Arterial Spin-Labeling MRI
The authors evaluated 15 children treated by indirect cerebral revascularization with multiple burr-holes between 2011–2013. Arterial spin-labeling MR imaging and T1 sequences were analyzed under SPM8 before and after the operation (3 and 12 months). Group analysis showed statistically significant preoperative hypoperfusion in the MCA territory in the Moyamoya hemispheres and a significant increase of cerebral perfusion in the same territory after revascularization. The authors conclude that SPM analysis of arterial spin-labeling MR imaging offers a noninvasive evaluation of preoperative cerebral hemodynamic impairment and an objective assessment of postoperative improvement in children with Moyamoya disease.
- Presurgical Assessment of the Sensorimotor Cortex Using Resting-State fMRI
Task-based approaches to functional localization of the motor cortex have limitations such as long scanning times and exclusion of patients with severe functional or neurologic disabilities and children. Resting-state fMRI may avoid these difficulties because patients do not perform any goal-directed tasks. Nineteen patients were prospectively evaluated by using task-based and resting-state fMRI to localize sensorimotor function. Independent component analyses were performed to generate spatial independent components reflecting functional brain networks or noise. The motor cortex was successfully and consistently identified by using resting-state fMRI. Hand, foot, and face regions were defined in a comparable fashion with task-based fMRI.