Radiomics Based Differentiation of Glioblastoma and Metastatic Disease: Impact of Different T1-Contrast Enhanced Sequences on Radiomic Features and Model Performance

From the Department of Radiology (G.B., C.G.Z.), University of Iowa Hospitals and Clinics, Iowa City, IA, USA; Division of Neuroradiology (G.B.), Department of Radiology, Mayo Clinic, Rochester, MN, USA, Division of Clinical Trials and Biostatistics (N.L.), Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA, College of Engineering (Y.L., H.Z., N.H.L., M.S.), University of Iowa, Iowa City, IA, USA, Division of Neuroradiology (A.K.A., N.S.), Department of Radiology, Mayo Clinic, Jacksonville, FL

From the Department of Radiology (G.B., C.G.Z.), University of Iowa Hospitals and Clinics, Iowa City, IA, USA; Division of Neuroradiology (G.B.), Department of Radiology, Mayo Clinic, Rochester, MN, USA, Division of Clinical Trials and Biostatistics (N.L.), Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA, College of Engineering (Y.L., H.Z., N.H.L., M.S.), University of Iowa, Iowa City, IA, USA, Division of Neuroradiology (A.K.A., N.S.), Department of Radiology, Mayo Clinic, Jacksonville, FL

From the Department of Radiology (G.B., C.G.Z.), University of Iowa Hospitals and Clinics, Iowa City, IA, USA; Division of Neuroradiology (G.B.), Department of Radiology, Mayo Clinic, Rochester, MN, USA, Division of Clinical Trials and Biostatistics (N.L.), Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA, College of Engineering (Y.L., H.Z., N.H.L., M.S.), University of Iowa, Iowa City, IA, USA, Division of Neuroradiology (A.K.A., N.S.), Department of Radiology, Mayo Clinic, Jacksonville, FL

From the Department of Radiology (G.B., C.G.Z.), University of Iowa Hospitals and Clinics, Iowa City, IA, USA; Division of Neuroradiology (G.B.), Department of Radiology, Mayo Clinic, Rochester, MN, USA, Division of Clinical Trials and Biostatistics (N.L.), Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA, College of Engineering (Y.L., H.Z., N.H.L., M.S.), University of Iowa, Iowa City, IA, USA, Division of Neuroradiology (A.K.A., N.S.), Department of Radiology, Mayo Clinic, Jacksonville, FL

From the Department of Radiology (G.B., C.G.Z.), University of Iowa Hospitals and Clinics, Iowa City, IA, USA; Division of Neuroradiology (G.B.), Department of Radiology, Mayo Clinic, Rochester, MN, USA, Division of Clinical Trials and Biostatistics (N.L.), Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA, College of Engineering (Y.L., H.Z., N.H.L., M.S.), University of Iowa, Iowa City, IA, USA, Division of Neuroradiology (A.K.A., N.S.), Department of Radiology, Mayo Clinic, Jacksonville, FL

From the Department of Radiology (G.B., C.G.Z.), University of Iowa Hospitals and Clinics, Iowa City, IA, USA; Division of Neuroradiology (G.B.), Department of Radiology, Mayo Clinic, Rochester, MN, USA, Division of Clinical Trials and Biostatistics (N.L.), Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA, College of Engineering (Y.L., H.Z., N.H.L., M.S.), University of Iowa, Iowa City, IA, USA, Division of Neuroradiology (A.K.A., N.S.), Department of Radiology, Mayo Clinic, Jacksonville, FL

From the Department of Radiology (G.B., C.G.Z.), University of Iowa Hospitals and Clinics, Iowa City, IA, USA; Division of Neuroradiology (G.B.), Department of Radiology, Mayo Clinic, Rochester, MN, USA, Division of Clinical Trials and Biostatistics (N.L.), Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA, College of Engineering (Y.L., H.Z., N.H.L., M.S.), University of Iowa, Iowa City, IA, USA, Division of Neuroradiology (A.K.A., N.S.), Department of Radiology, Mayo Clinic, Jacksonville, FL

From the Department of Radiology (G.B., C.G.Z.), University of Iowa Hospitals and Clinics, Iowa City, IA, USA; Division of Neuroradiology (G.B.), Department of Radiology, Mayo Clinic, Rochester, MN, USA, Division of Clinical Trials and Biostatistics (N.L.), Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA, College of Engineering (Y.L., H.Z., N.H.L., M.S.), University of Iowa, Iowa City, IA, USA, Division of Neuroradiology (A.K.A., N.S.), Department of Radiology, Mayo Clinic, Jacksonville, FL

From the Department of Radiology (G.B., C.G.Z.), University of Iowa Hospitals and Clinics, Iowa City, IA, USA; Division of Neuroradiology (G.B.), Department of Radiology, Mayo Clinic, Rochester, MN, USA, Division of Clinical Trials and Biostatistics (N.L.), Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA, College of Engineering (Y.L., H.Z., N.H.L., M.S.), University of Iowa, Iowa City, IA, USA, Division of Neuroradiology (A.K.A., N.S.), Department of Radiology, Mayo Clinic, Jacksonville, FL