Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • Quality, Safety, and Value Special Collection
    • ASFNR Stroke Perfusion Special Collection
    • ASNR Foundation Special Collection
    • Advancing NeuroMRI with High-Relaxivity Contrast Agents
    • Low-Field MRI
    • Alzheimer Disease
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Author Policies
    • Peer-Review Policy
    • Transparency in Authorship Policy
    • Conflict-of-Interest Policy
    • Statistical Tips
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • Quality, Safety, and Value Special Collection
    • ASFNR Stroke Perfusion Special Collection
    • ASNR Foundation Special Collection
    • Advancing NeuroMRI with High-Relaxivity Contrast Agents
    • Low-Field MRI
    • Alzheimer Disease
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Author Policies
    • Peer-Review Policy
    • Transparency in Authorship Policy
    • Conflict-of-Interest Policy
    • Statistical Tips
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

Check out our Case Collections, Special Collections, and more. Read the latest AJNR updates


Improved Turnaround Times | Median time to first decision: 12 days

Photon-Counting CT

We are excited to present this special collection focused on the emerging field of photon-counting CT (PCCT), sponsored by Siemens Healthineers. This collection highlights the transformative potential of PCCT, which is poised to redefine the landscape of neuroimaging and head and neck diagnostics. As the technology evolves, it offers unparalleled advancements in image resolution, precision, and clinical applicability—transformations that are set to benefit both diagnostic radiology and patient care in profound ways.

Photon-counting CT is a cutting-edge modality that goes beyond the limitations of traditional energy-integrating detectors. With the ability to count individual photons, this technology offers significant improvements in spatial and contrast resolution, enabling the detailed visualization of fine anatomic structures that were previously challenging to capture. It also promises to provide better tissue differentiation, enhancing our ability to detect subtle abnormalities in both soft tissues and bony structures. Beyond this, its ability to reduce radiation dose without compromising image quality is one of its most compelling advantages, offering a safer imaging alternative—especially for pediatric and sensitive patient populations.

The contributions in this special issue reflect the breadth of this technology’s application, from its use in highly detailed imaging of the temporal bone to its potential for improved neurovascular imaging. As we continue to explore and push the boundaries of photon-counting CT, it is becoming increasingly clear that its role in advancing diagnostic imaging is not limited to structural imaging alone, but extends to dynamic and functional applications as well.

This collection provides a comprehensive overview of the current state of photon-counting CT, showcasing its potential not only to improve diagnostic accuracy but also to pave the way for new clinical possibilities. With its ability to offer clearer, more detailed images at lower doses, photon-counting CT stands at the threshold of a new era in medical imaging. As the technology continues to evolve, we anticipate that it will become a central tool in clinical practice, particularly in neuroimaging, otology, and beyond.

We hope this collection sparks further exploration into the potential of photon-counting CT and serves as an invaluable resource for both clinicians and researchers interested in this groundbreaking advancement. It is an exciting time for medical imaging, and we look forward to the continued development of this transformative technology.

Max Wintermark, MD
Editor-in-Chief, AJNR


  • Photon-counting detector CT of the brain reduces variability of Hounsfield units and has a mean offset compared with energy-integrating detector CT

    Thomas Stein, Friederike Lang, Stephan Rau, Marco Reisert, Maximilian. F. Russe, Till Schürmann, Anna Fink, Elias Kellner, Jakob Weiss, Fabian Bamberg, Horst Urbach, Alexander Rau

    Journal Article | American Journal of Neuroradiology Date: 1-Jul-2025 DOI: 10.3174/ajnr.A8910

  • Pituitary Photon Counting Detector CT for Cushing Disease: Pre-operative Lesion Localization, Intraoperative Findings, and Post-operative Outcomes

    Ian T Mark, Giorgos Michalopoulos, Jamie Van Gompel, Maria Peris Celda, Irina Bancos, Diane Donegan, Lucinda M. Gruber, Dana Erickson, Alex A. Nagelschneider, Lifeng Yu

    Journal Article | American Journal of Neuroradiology Date: 23-Jun-2025 DOI: 10.3174/ajnr.A8893

  • Optimization of Photon-Counting CT Myelography for the Detection of CSF-Venous Fistulas Using Convolutional Neural Network Denoising: A Comparative Analysis of Reconstruction Techniques

    Ajay A. Madhavan, Zhongxing Zhou, Paul J. Farnsworth, Jamison Thorne, Timothy J. Amrhein, Peter G. Kranz, Waleed Brinjikji, Jeremy K. Cutsforth-Gregory, Michelle L. Kodet, Nikkole M. Weber, Grace Thompson, Felix E. Diehn, Lifeng Yu

    Journal Article | American Journal of Neuroradiology Date: 19-Jun-2025 DOI: 10.3174/ajnr.A8695

  • Ultra-High-Resolution Photon-Counting-Detector CT with a Dedicated Denoising Convolutional Neural Network for Enhanced Temporal Bone Imaging

    Shaojie Chang, John C. Benson, John I. Lane, Michael R. Bruesewitz, Joseph R. Swicklik, Jamison E. Thorne, Emily K. Koons, Matthew L. Carlson, Cynthia H. McCollough, Shuai Leng

    Journal Article | American Journal of Neuroradiology Date: 3-Jun-2025 DOI: 10.3174/ajnr.A8572

  • Photon-Counting CT Myelography for the Detection of Spinal CSF Leaks

    Ajay A. Madhavan, Peter G. Kranz, Waleed Brinjikji, Ian T. Mark, Timothy J. Amrhein

    Journal Article | American Journal of Neuroradiology Date: 2-Apr-2025 DOI: 10.3174/ajnr.A8736

  • Pre- and Postoperative Imaging of Cochlear Implantation in Cadaveric Specimens Using Low-Dose Photon-Counting Detector CT

    Bjoern Spahn, Franz-Tassilo Müller-Graff, Kristen Rak, Jonas Engert, Johannes Voelker, Stephan Hackenberg, Rudolf Hagen, Tilmann Neun, Bernhard Petritsch, Thorsten Alexander Bley, Jan-Peter Grunz, Henner Huflage

    Journal Article | American Journal of Neuroradiology Date: 3-Feb-2025 DOI: 10.3174/ajnr.A8533

  • Comprehensive Review of Inner Ear Anatomy on Photon-Counting CT

    Dinesh Rao, John V. Murray, Amit K. Agarwal, Sukhwinder Johnny Sandhu, Pat A. Rhyner

    Journal Article | American Journal of Neuroradiology Date: 14-Nov-2024 DOI: 10.3174/ajnr.A8410

  • Optimizing Photon-Counting Detector CT for Imaging Intracranial Aneurysms

    Kishore Rajendran, Ajay A. Madhavan

    Journal Article | American Journal of Neuroradiology Date: 3-Oct-2024 DOI: 10.3174/ajnr.A8400

  • High-Resolution Head CTA: A Prospective Patient Study Comparing Image Quality of Photon-Counting Detector CT and Energy-Integrating Detector CT

    Felix E. Diehn, Zhongxing Zhou, Jamison E. Thorne, Norbert G. Campeau, Alex A. Nagelschneider, Laurence J. Eckel, John C. Benson, Ajay A. Madhavan, Girish Bathla, Vance T. Lehman, Nathan R. Huber, Francis Baffour, Joel G. Fletcher, Cynthia H. McCollough, Lifeng Yu

    Journal Article | American Journal of Neuroradiology Date: 3-Oct-2024 DOI: 10.3174/ajnr.A8342

  • Neurovascular Imaging with Ultra-High-Resolution Photon-Counting CT: Preliminary Findings on Image-Quality Evaluation

    Adrienn Tóth, Justin A. Chetta, Milad Yazdani, M. Gisele Matheus, Jim O‘Doherty, Sameer V. Tipnis, M. Vittoria Spampinato

    Journal Article | American Journal of Neuroradiology Date: 3-Oct-2024 DOI: 10.3174/ajnr.A8350

  • Comparison of Image Quality and Radiation Dose in Pediatric Temporal Bone CT Using Photon-Counting Detector CT and Energy-Integrating Detector CT

    Jeong Sub Lee, John Kim, Jayapalli R. Bapuraj, Ashok Srinivasan

    Journal Article | American Journal of Neuroradiology Date: 9-Sep-2024 DOI: 10.3174/ajnr.A8276

  • Photon-Counting CT in the Head and Neck: Current Applications and Future Prospects

    John C. Benson, Norbert G. Campeau, Felix E. Diehn, John I. Lane, Shuai Leng, Gul Moonis, on behalf of the ASHNR Research Committee

    Journal Article | American Journal of Neuroradiology Date: 9-Aug-2024 DOI: 10.3174/ajnr.A8265

  • Back to the Future: Dynamic Contrast-Enhanced Photon-Counting Detector CT for the Detection of Pituitary Adenoma in Cushing Disease

    Ian T. Mark, Jamie Van Gompel, Irina Bancos, Alex A. Nagelschneider, Derek R. Johnson, Girish Bathla, Ajay A. Madhavan, Nikkole M. Weber, Lifeng Yu

    Journal Article | American Journal of Neuroradiology Date: 7-Jun-2024 DOI: 10.3174/ajnr.A8171

  • Comprehensive Review of External and Middle Ear Anatomy on Photon Counting CT

    Dinesh Rao, John V. Murray, Amit K. Agarwal, Sukhwinder Johnny Sandhu, Pat A. Rhyner

    Journal Article | American Journal of Neuroradiology Date: 28-May-2024 DOI: 10.3174/ajnr.A8359

  • Benefits of Photon-Counting CT Myelography for Localization of Dural Tears in Spontaneous Intracranial Hypotension

    Ajay A. Madhavan, Jeremy K. Cutsforth-Gregory, Waleed Brinjikji, John C. Benson, Ben A. Johnson-Tesch, Greta B. Liebo, Ian T. Mark, Michael P. Oien, Darya P. Shlapak, Lifeng Yu, Jared T. Verdoorn

    Journal Article | American Journal of Neuroradiology Date: 9-May-2024 DOI: 10.3174/ajnr.A8179

  • Application of a Denoising High-Resolution Deep Convolutional Neural Network to Improve Conspicuity of CSF-Venous Fistulas on Photon-Counting CT Myelography

    Ajay A. Madhavan, Jeremy K. Cutsforth-Gregory, Waleed Brinjikji, John C. Benson, Felix E. Diehn, Ian T. Mark, Jared T. Verdoorn, Zhongxing Zhou, Lifeng Yu

    Journal Article | American Journal of Neuroradiology Date: 29-Dec-2023 DOI: 10.3174/ajnr.A8097

  • Discrimination of Hemorrhage and Contrast Media in a Head Phantom on Photon-Counting Detector CT Data

    Franka Risch, Ansgar Berlis, Thomas Kroencke, Florian Schwarz, Christoph J. Maurer

    Journal Article | American Journal of Neuroradiology Date: 28-Dec-2023 DOI: 10.3174/ajnr.A8093

  • Diagnostic Performance of Decubitus Photon-Counting Detector CT Myelography for the Detection of CSF-Venous Fistulas

    Ajay A. Madhavan, Jeremy K. Cutsforth-Gregory, Waleed Brinjikji, Girish Bathla, John C. Benson, Felix E. Diehn, Laurence J. Eckel, Ian T. Mark, Pearse P. Morris, Melissa A. Payne, Jared T. Verdoorn, Nikkole M. Weber, Lifeng Yu, Francis Baffour, Joel G. Fletcher, Cynthia H. McCollough

    Journal Article | American Journal of Neuroradiology Date: 11-Dec-2023 DOI: 10.3174/ajnr.A8040

  • Utility of Photon-Counting Detector CT Myelography for the Detection of CSF-Venous Fistulas

    A.A. Madhavan, L. Yu, W. Brinjikji, J.K. Cutsforth-Gregory, F.R. Schwartz, I.T. Mark, J.C. Benson, T.J. Amrhein

    Journal Article | American Journal of Neuroradiology Date: 8-Jun-2023 DOI: 10.3174/ajnr.A7887

  • A New Frontier in Temporal Bone Imaging: Photon-Counting Detector CT Demonstrates Superior Visualization of Critical Anatomic Structures at Reduced Radiation Dose

    J.C. Benson, K. Rajendran, J.I. Lane, F.E. Diehn, N.M. Weber, J.E. Thorne, N.B. Larson, J.G. Fletcher, C.H. McCollough, S. Leng

    Journal Article | American Journal of Neuroradiology Date: 8-Apr-2022 DOI: 10.3174/ajnr.A7452

In this issue

American Journal of Neuroradiology: 47 (1)
American Journal of Neuroradiology
Vol. 47, Issue 1
1 Jan 2026
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Sign up for alerts
Advertisement
Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Peer-Review Policy
  • Transparency in Authorship Policy
  • Conflict-of-Interest Policy
  • News and Updates
  • Become a Reviewer/Academy of Reviewers

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2026 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire