RT Journal Article
SR Electronic
T1 A Novel Method of Thrombus Preparation for Use in a Swine Model for Evaluation of Thrombectomy Devices
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1741
OP 1743
DO 10.3174/ajnr.A1991
VO 31
IS 9
A1 Kan, I.
A1 Yuki, I.
A1 Murayama, Y.
A1 Viñuela, F.A.
A1 Kim, R.H.
A1 Vinters, H.V.
A1 Viñuela, F.
YR 2010
UL http://www.ajnr.org/content/31/9/1741.abstract
AB We report the development of a novel technique of thrombus preparation for use in a swine model for evaluation of thrombectomy devices. The experimental thrombus prepared using plain sedimentation showed mechanical stability due to its solid fibrin-rich component. The thrombus also showed histologic similarity to the typical thromboemboli recovered from patients with stroke in the course of therapeutic thrombectomy. This new technique may be beneficial for preclinical evaluation of thrombectomy devices.