PT  - JOURNAL ARTICLE
AU  - Tao, S.
AU  - Zhou, X.
AU  - Greco, E.
AU  - Gupta, V.
AU  - Freund, B.E.
AU  - Westerhold, E.M.
AU  - Feyissa, A.M.
AU  - Tatum, W.O.
AU  - Grewal, S.
AU  - Patel, V.
AU  - Middlebrooks, E.H.
TI  - Edge-Enhancing Gradient-Echo MP2RAGE for Clinical Epilepsy Imaging at 7T
AID  - 10.3174/ajnr.A7782
DP  - 2023 Feb 02
TA  - American Journal of Neuroradiology
4099  - http://www.ajnr.org/content/early/2023/02/02/ajnr.A7782.short
4100  - http://www.ajnr.org/content/early/2023/02/02/ajnr.A7782.full
AB  - SUMMARY: The 3D edge-enhancing gradient-echo (EDGE) MR imaging sequence offers superior contrast-to-noise ratio in the detection of focal cortical dysplasia. EDGE could benefit from 7T MR imaging but also faces challenges such as image inhomogeneity and low acquisition efficiency. We propose an EDGE-MP2RAGE sequence that can provide both EDGE and T1-weighted contrast, simultaneously, improving data-acquisition efficiency. We demonstrate that with sequence optimization, EDGE images with sufficient uniformity and T1-weighted images with high gray-to-white matter contrast can be achieved.CNRcontrast-to-noise ratioEDGEedge-enhancing gradient-echoFCDfocal cortical dysplasiaINVinversion imaging