RT Journal Article
SR Electronic
T1 Edge-Enhancing Gradient-Echo MP2RAGE for Clinical Epilepsy Imaging at 7T
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 268
OP 270
DO 10.3174/ajnr.A7782
VO 44
IS 3
A1 S. Tao
A1 X. Zhou
A1 E. Greco
A1 V. Gupta
A1 B.E. Freund
A1 E.M. Westerhold
A1 A.M. Feyissa
A1 W.O. Tatum
A1 S. Grewal
A1 V. Patel
A1 E.H. Middlebrooks
YR 2023
UL http://www.ajnr.org/content/44/3/268.abstract
AB SUMMARY: The 3D edge-enhancing gradient-echo (EDGE) MR imaging sequence offers superior contrast-to-noise ratio in the detection of focal cortical dysplasia. EDGE could benefit from 7T MR imaging but also faces challenges such as image inhomogeneity and low acquisition efficiency. We propose an EDGE-MP2RAGE sequence that can provide both EDGE and T1-weighted contrast, simultaneously, improving data-acquisition efficiency. We demonstrate that with sequence optimization, EDGE images with sufficient uniformity and T1-weighted images with high gray-to-white matter contrast can be achieved.CNRcontrast-to-noise ratioEDGEedge-enhancing gradient-echoFCDfocal cortical dysplasiaINVinversion imaging