PT  - JOURNAL ARTICLE
AU  - Sagiuchi, Takao
AU  - Ishii, Katsumi
AU  - Utsuki, Satoshi
AU  - Asano, Yuuji
AU  - Tsukahara, Shinya
AU  - Kan, Shinichi
AU  - Fujii, Kiyotaka
AU  - Hayakawa, Kazushige
TI  - Increased Uptake of Technetium-99m-Hexamethylpropyleneamine Oxime Related to Primary Leptomeningeal Melanoma
DP  - 2002 Sep 01
TA  - American Journal of Neuroradiology
PG  - 1404--1406
VI  - 23
IP  - 8
4099  - http://www.ajnr.org/content/23/8/1404.short
4100  - http://www.ajnr.org/content/23/8/1404.full
SO  - Am. J. Neuroradiol.2002 Sep 01; 23
AB  - Summary: We present an autopsy case of primary leptomeningeal melanoma visualized with technetium-99m-hexamethylpropyleneamine oxime (Tc-99m-HMPAO) single photon emission CT (SPECT) of the brain. Increased uptake of Tc-99m-HMPAO coincided with leptomeningeal enhancement on MR images and with the tumor location of the autopsy findings. It was thought that Tc-99m-HMPAO could correlate closely with melanoma. Tc-99m-HMPAO SPECT clearly showed primary leptomeningeal melanoma and severe hypoperfusion induced by intracranial hypertension and tumor proliferation.