PT  - JOURNAL ARTICLE
AU  - Hassan, Tamer
AU  - Ezura, Masayuki
AU  - Timofeev, Eugene V.
AU  - Tominaga, Teiji
AU  - Saito, Tsutomu
AU  - Takahashi, Akira
AU  - Takayama, Kazuyoshi
AU  - Yoshimoto, Takashi
TI  - Computational Simulation of Therapeutic Parent Artery Occlusion to Treat Giant Vertebrobasilar Aneurysm
DP  - 2004 Jan 01
TA  - American Journal of Neuroradiology
PG  - 63--68
VI  - 25
IP  - 1
4099  - http://www.ajnr.org/content/25/1/63.short
4100  - http://www.ajnr.org/content/25/1/63.full
SO  - Am. J. Neuroradiol.2004 Jan 01; 25
AB  - Summary: We applied computational fluid dynamics (CFD) analysis to assess 3D digital subtraction angiography findings in a patient with a giant vertebrobasilar aneurysm to simulate and compare the consequences of left and right vertebral artery occlusion. The balloon occlusion test suggested that occlusion of the right vertebral artery is the better way to treat this patient’s aneurysm from the point of view of aneurysmal thrombosis and isolation from the circulation. The computer simulation supported this conclusion, at the same time indicating that from the point of view of pressure distribution on the wall of the aneurysm, the right vertebral occlusion may be also accompanied by an undesirable effect. A high-pressure area on the aneurysm wall in systole was revealed. This high pressure potentially could lead to subsequent aneurysmal growth, which indeed occurred, as was revealed by a follow-up examination 6 months later. This study is a good example of possible future applications of CFD in patients with cerebrovascular disease before therapeutic intervention.