RT Journal Article
SR Electronic
T1 Familial Amyloid Polyneuropathy: Hypertrophy of Ligaments Supporting the Spinal Cord
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1599
OP 1602
VO 25
IS 9
A1 Mika Kitajima
A1 Yukunori Korogi
A1 Masayuki Yamura
A1 Ichiro Ikushima
A1 Yoshiko Hayashida
A1 Yukio Ando
A1 Makoto Uchino
A1 Yasuyuki Yamashita
YR 2004
UL http://www.ajnr.org/content/25/9/1599.abstract
AB Summary: We describe characteristic spinal MR findings of two cases of familial amyloid polyneuropathy (FAP). Both cases showed leptomeningeal enhancement on contrast-enhanced T1-weighted image. In addition, three-dimensional constructive interference in steady-state imaging demonstrated thickening of the ligaments, other connective tissues within the spinal canal, dura matter, and dorsal nerve roots. These findings in FAP are felt to represent amyloid deposition.