RT Journal Article
SR Electronic
T1 Early Characteristics of Sturge-Weber Syndrome Shown by Perfusion MR Imaging and Proton MR Spectroscopic Imaging
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1912
OP 1915
VO 24
IS 9
A1 Lin, Doris D.M.
A1 Barker, Peter B.
A1 Kraut, Michael A.
A1 Comi, Anne
YR 2003
UL http://www.ajnr.org/content/24/9/1912.abstract
AB Summary: We report the case of a 9-month-old boy with Sturge-Weber syndrome and new onset of seizure. Perfusion MR imaging showed early changes compatible with impaired venous drainage in the affected hemisphere, whereas proton MR spectroscopic imaging revealed a focal parietal area of elevated choline without significant alteration of N-acetylaspartate levels. The perfusion and subtle metabolic abnormalities are comparable with the extent of the overlying leptomeningeal enhancement, illustrating the early pathophysiological manifestation of this disease.