TY - JOUR T1 - MR Imaging and Spectroscopy of a Tuber Cinereum Hamartoma in a Patient with Growth Hormone Deficiency and Hypogonadotropic Hypogonadism JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 1177 LP - 1180 VL - 24 IS - 6 AU - David D. Martin AU - Uwe Seeger AU - Michael B. Ranke AU - Wolfgang Grodd Y1 - 2003/06/01 UR - http://www.ajnr.org/content/24/6/1177.abstract N2 - Summary: To our knowledge, this is the first report of hypogonadotropic hypogonadism, or growth hormone deficiency, in a patient without non-Pallister-Hall syndrome who had hypothalamic hamartoma diagnosed on the basis of MR imaging and MR spectroscopy findings. On short-TE proton MR spectra, the N-acetylaspartate concentration in the hamartoma was lower than that in the thalamus but similar to that in the amygdala. However, myo-inositol concentration was elevated in the hamartoma compared with that in the amygdala and thalamus. This report stresses the advantages of short-TE spectroscopy and demonstrates that regional variations in spectra should be considered when reference structures are used. ER -