RT Journal Article
SR Electronic
T1 Diffusion-Weighted MR Imaging in Neonatal Nonketotic Hyperglycinemia
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1181
OP 1183
VO 24
IS 6
A1 Pek-Lan Khong
A1 Barbara C. C. Lam
A1 Brian H. Y. Chung
A1 Ka-Yin Wong
A1 Gaik-Cheng Ooi
YR 2003
UL http://www.ajnr.org/content/24/6/1181.abstract
AB Summary: To our knowledge, we are the first to report the diffusion-weighted MR imaging findings in a 15-day-old neonate with nonketotic hyperglycinemia. We found bilaterally symmetrical lesions of restricted diffusion in the dorsal brain stem, cerebral peduncles, and posterior limbs of the internal capsule, which were more conspicuous and extensive on diffusion-weighted MR images than on T2-weighted images. These lesions are in the myelinated tracts of the neonate and are compatible with the expected sites of abnormality in vacuolating myelinopathy.