PT  - JOURNAL ARTICLE
AU  - Stuart C. Coley
AU  - David A. Porter
AU  - Fernando Calamante
AU  - Wui K. Chong
AU  - Alan Connelly
TI  - Quantitative MR Diffusion Mapping and Cyclosporine-Induced Neurotoxicity
DP  - 1999 Sep 01
TA  - American Journal of Neuroradiology
PG  - 1507--1510
VI  - 20
IP  - 8
4099  - http://www.ajnr.org/content/20/8/1507.short
4100  - http://www.ajnr.org/content/20/8/1507.full
SO  - Am. J. Neuroradiol.1999 Sep 01; 20
AB  - Summary: Apparent diffusion coefficient maps of two patients with cyclosporine-induced neurotoxicity showed areas of increased diffusion that corresponded to the characteristic regions of signal change on routine T2-weighted sequences. The majority of lesions subsequently resolved without residual T2 or diffusion signal alteration. These findings suggest that, in our patients, the neurotoxic effects of cyclosporine resulted in a partially reversible extravasation of fluid into the cerebral interstitium and were not associated with acute ischemia.