%0 Journal Article %A Naohiro Tsuyuguchi %A Yoshimi Matsuoka %A Ichiro Sunada %A Yasuhiro Matsusaka %A Moududul Haque %T Evaluation of Pleomorphic Xanthoastrocytoma by Use of Positron Emission Tomography with [18-F]-Fluorodeoxyglucose and [11C]-Methionine Tracers %D 2001 %J American Journal of Neuroradiology %P 311-313 %V 22 %N 2 %X Summary: We present a case of pleomorphic xanthoastrocytoma (PXA) in a patient with temporal lobe seizures. Imaging sequences included MR, and results of positron emission tomography (PET) with [18F]-fluorodeoxyglucose (FDG) and [11C]-methionine (Met) tracers revealed a hypermetabolic region equivalent or nearly equivalent to normal cerebral cortex, suggesting that the tumor might have malignant potential. Histopathologic findings indicated low-grade glioma. The mechanism for glucose hypermetabolic activity of PXA is not clear; however, the positive findings obtained from FDG-PET may not always indicate the degree of malignancy associated with PXA. %U https://www.ajnr.org/content/ajnr/22/2/311.full.pdf