RT Journal Article
SR Electronic
T1 Novel Proximal 14q Deletion: Clinical and Diffusion Tensor Imaging Tractography Findings in a Patient with Lissencephaly, Agenesis of the Corpus Callosum, and Septo-Optic Dysplasia
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP E16
OP E18
DO 10.3174/ajnr.A2745
VO 33
IS 2
A1 Bravo, E.K.
A1 White, M.L.
A1 Olney, A.H.
A1 McAllister, J.L.
A1 Zhang, Y.D.
YR 2012
UL http://www.ajnr.org/content/33/2/E16.abstract
AB SUMMARY: We report the unique CNS findings in a patient with a proximal chromosome 14q interstitial deletion. Conventional MR imaging allowed the clear delineation of agenesis of the corpus callosum, SOD, and diffuse lissencephaly. DTI tractography played a significant role in the evaluation of the proximal 14q deletion−associated abnormalities, delineating the extent of the dysmorphic connections of the Probst bundles and clarifying that apparent areas of heterotopias were the corticospinal tracts. FAfractional anisotropySODsepto-optic dysplasia