PT  - JOURNAL ARTICLE
AU  - Gafton, A.R.
AU  - Glastonbury, C.M.
AU  - Eastwood, J.D.
AU  - Hoang, J.K.
TI  - Parathyroid Lesions: Characterization with Dual-Phase Arterial and Venous Enhanced CT of the Neck
AID  - 10.3174/ajnr.A2885
DP  - 2012 May 01
TA  - American Journal of Neuroradiology
PG  - 949--952
VI  - 33
IP  - 5
4099  - http://www.ajnr.org/content/33/5/949.short
4100  - http://www.ajnr.org/content/33/5/949.full
SO  - Am. J. Neuroradiol.2012 May 01; 33
AB  - SUMMARY: This clinical report describes the enhancement characteristics of hypersecreting parathyroid lesions on dual-phase neck CT. We retrospectively analyzed the enhancement characteristics of 5 pathologically confirmed PTH-secreting lesions on dual-phase CT examinations. Attenuation values were measured for PTH-secreting lesions, vascular structures (CCA and IJV), and soft tissue structures (thyroid gland, jugulodigastric lymph node, and submandibular gland). From the attenuation values, “relative enhancement washout percentage” and “tissue-vascular ratio” were calculated and compared. All lesions decreased in attenuation from arterial to venous phase, while the mean attenuation values of other soft tissue structures increased. A high relative enhancement washout percentage was correlated with parathyroid lesions (P < .006). The tissue-CCA ratio and tissue-IJV ratio for PTH-secreting lesions in the arterial phase were statistically significantly higher compared with soft tissue structures (P < .05). If these results are validated in future larger studies, noncontrast and delayed venous phases of 4D-CT could be eliminated to markedly reduce radiation exposure. CCAcommon carotid arteryHUHounsfield unitsIJVinternal jugular veinPTHparathyroid hormoneROCreceiver operating characteristic curve