@article {Hwang1676, author = {G. Hwang and E.-A. Jeong and J.H. Sohn and H. Park and J.S. Bang and S.-C. Jin and B.C. Kim and C.W. Oh and O.-K. Kwon}, title = {The Characteristics and Risk Factors of Headache Development after the Coil Embolization of an Unruptured Aneurysm}, volume = {33}, number = {9}, pages = {1676--1678}, year = {2012}, doi = {10.3174/ajnr.A3018}, publisher = {American Journal of Neuroradiology}, abstract = {BACKGROUND AND PURPOSE: Development of a headache after aneurysm coil embolization is not uncommon but has received little attention. The authors prospectively analyze the characteristics and risk factors of a headache after coiling in patients treated for an unruptured cerebral aneurysm. MATERIALS AND METHODS: Ninety patients treated for an unruptured cerebral aneurysm over a period of 1 year, and without a headache history within a month before coiling, were enrolled in this study. All coilings were successfully performed without neurologic complications. After coiling, headache development and intensities were recorded. RESULTS: Fifty (55.6\%) patients experienced a headache (VAS score, 4.5 {\textpm} 2.02) at 7.9 (range, 0{\textendash}72) hours, on average, after coiling, and all headaches resolved within an average of 73.0 (range, 3{\textendash}312) hours. Univariate analysis showed that the following were significantly associated with the development of a headache: age <=50 years (OR 4.636, 95\% CI, 1.414{\textendash}15.198), hypertension (OR 0.232, 95\% CI, 0.095{\textendash}0.571), a packing attenuation of \>25\% (OR 3.619, 95\% CI, 1.428{\textendash}9.174), and a previous headache history (OR 2.769, 95\% CI, 1.120{\textendash}6.849). However, binary logistic regression showed that only a packing attenuation of \>25\% (P = .013, adjusted OR 3.774, 95\% CI, 1.320{\textendash}10.790) and no history of hypertension (P = .019, adjusted OR 3.515, 95\% CI, 1.233{\textendash}10.021) were independently associated with the development of a headache. CONCLUSIONS: A headache frequently developed after the coiling of unruptured aneurysms. However, headaches were relatively benign and resolved within several days. The present study shows that no hypertension history and a packing attenuation of \>25\% are risk factors of headache development. CIconfidence intervalNSAIDnonsteroidal anti-inflammatory drugORodds ratioVASVisual Analogue Scale}, issn = {0195-6108}, URL = {https://www.ajnr.org/content/33/9/1676}, eprint = {https://www.ajnr.org/content/33/9/1676.full.pdf}, journal = {American Journal of Neuroradiology} }